This listing was ended by the seller because the item is no longer available.
 
Posts to:
Worldwide See exclusions
Delivery:
Visit store:
eBay Stores The Book Depository
FREE postage
 
Posts to:
Worldwide See exclusions

Analysis of Aggregates and Particles in Protein Ph.....

See original listing
Analysis-of-Aggregates-and-Particles-in-Protein-Ph
Item Ended
Item condition:
Brand new
Ended:
21 Feb, 2013 05:30:52 AEDST
Price:
AU $126.08
Postage:
FREE Standard delivery from outside AU | See details
Item location:
Gloucester, UK, United Kingdom
Seller:

Description

Item number:
180906240554
Seller assumes all responsibility for this listing.
Last updated on  23 Jan, 2013 10:01:35 AEDST  View all revisions

Item specifics

Condition:
Brand new: A new, unread, unused book in perfect condition with no missing or damaged pages. See the seller's listing for full details. See all condition definitions- opens in a new window or tab ... Read moreabout the condition
Publisher: John Wiley and Sons Ltd
ISBN: 9780470497180

Detailed item info

Description
This book describes how to address the analysis of aggregates and particles in protein pharmaceuticals, provides a comprehensive overview of current methods and integrated approaches used to quantify and characterize aggregates and particles, and discusses regulatory requirements.

Key Features
PublisherJohn Wiley and Sons Ltd
Date of Publication22/10/2010
LanguageEnglish
FormatHardback
ISBN-100470497181
ISBN-139780470497180
SubjectChemistry

Publication Data
Place of PublicationChicester
Country of PublicationUnited Kingdom
ImprintWiley-Blackwell (an imprint of John Wiley & Sons Ltd)
Content NoteIllustrations

Dimensions
Weight786 g
Width155 mm
Height240 mm
Spine29 mm

Credits
Edited byHanns-Christian Mahler, Wim Jiskoot

Description
Table Of ContentsContributors ix Preface xiii Glossary xv 1 The Critical Need for Robust Assays for Quantitation and Characterization of Aggregates of Therapeutic Proteins 1 John F. Carpenter, Barry Cherney, and Amy S. Rosenberg I METHODS USED FOR DETECTING, QUANTIFYING, AND SIZING OF PROTEIN AGGREGATES AND PARTICLES 9 2 Separation-Based Analytical Methods for Measuring Protein Aggregation 11 Jun Liu, Barthelemy Demeule, and Steven J. Shire 3 Laser Light Scattering-Based Techniques Used for the Characterization of Protein Therapeutics 37 John den Engelsman, Fabian Kebbel, and Patrick Garidel 4 Online Detection Methods and Emerging Techniques for Soluble Aggregates in Protein Pharmaceuticals 61 Tapan K. Das 5 Analytical Methods to Measure Subvisible Particulates 85 Shawn Cao, Linda Narhi, Yijia Jiang, and Rahul S. Rajan 6 Detection of Visible Particles in Parenteral Products 117 Ronald Smulders, Hans Vos, and Hanns-Christian Mahler 7 Characterization of Aggregates and Particles Using Emerging Techniques 133 Hui Zhao, Manuel Diez, Atanas Koulov, Mariola Bozova, Markus Bluemel, and Kurt Forrer II METHODS USED TO CHARACTERIZE PROTEIN AGGREGATES AND PARTICLES 169 8 Ultraviolet Absorption Spectroscopy 171 Reza Esfandiary and Charles Russell Middaugh 9 Fluorescence Spectroscopy to Characterize Protein Aggregates and Particles 201 Robert A. Poole, Andrea Hawe, Wim Jiskoot, and Kevin Braeckmans 10 Infrared Spectroscopy to Characterize Protein Aggregates 227 Marco van de Weert and Lene Jorgensen 11 Raman Microscopy for Characterization of Particles 249 Stefan Fischer, Oliver Valet, and Markus Lankers 12 Microscopic Methods for Particle Characterization in Protein Pharmaceuticals 269 Patrick Garidel, Andrea Herre, and Werner Kliche III INTEGRATED APPROACHES TO PROTEIN AGGREGATION AND PARTICLES 303 13 Comparison of Methods for Soluble Aggregate Detection and Size Characterization 305 John S. Philo 14 Protein Purification and Its Relation to Protein Aggregation and Particles 335 Roberto Falkenstein, Stefan Hepbildikler, Wolfgang Kuhne, Thorsten Lemm, Hans Rogl, Eva Rosenberg, Gerhard Winter, Frank Zettl, and Ralf Zippelius 15 Formulation Development and Its Relation to Protein Aggregation and Particles 369 Miriam Printz and Wolfgang Friess Index 389
Author BiographyHANNS-CHRISTIAN MAHLER is Head of Pharmaceutical and Device Development, Pharma Technical Development Biologics Europe at F. Hoffmann-La Roche Ltd. He is also Lecturer at the Institute for Pharmaceutical Technology at the University of Frankfurt/Main, Germany. WIM JISKOOT is Professor and Head of the Biologics Formulation Group in the Leiden/Amsterdam Center for Drug Research (LACDR) at Leiden University.

Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.

The Book Depository with availability on over a million titles

Analysis of Aggregates and Particles in Protein Ph.....

Description: Brand New Book with Free Worldwide Delivery. This book describes how to address the analysis of aggregates and particles in protein pharmaceuticals, provides a comprehensive overview of current methods and integrated approaches used to quantify and characterize aggregates and particles, and discusses regulatory requirements. Analytical methods covered in the book include separation, light scattering, microscopy, and spectroscopy.

Delivery information

We despatch via Royal Mail Priority Airmail. Please see below our approximate guide to how long you should expect for your books to reach you:

Australia 10 working days
Europe 7-10 working days
Rest of the World 7-10 working days
US and Canada 10- 14 working days
United Kingdom 3-5 working days

About us

The Book Depository is working to offer the largest range of titles in the world. We are an established bookseller with over eight years experience in getting books to readers all around the world. All our books are sent with free delivery. All our books are brand new. Please check description for additional details.

Contact us

Feel free to contact us about any issues you may have regarding your order. Please use the Seller contact form to get in touch. We aim to respond to you within 24 hours.

Questions and answers about this item

No questions or answers have been posted about this item.
Ask a question




Place bid

Time left:
Current bid:
(Approximately ##1##)
Shipping:
Import charges:
Your max bid:
Your max bid:
By clicking Confirm bid, you commit to buy this item from the seller if you are the winning bidder.
By clicking Confirm bid, you are committing to buy this item from the seller if you are the winning bidder and have read and agreed to the Global Postage Program terms and conditions - opens in a new window or tab. Import charges previously quoted are subject to change if you increase you maximum bid amount.
Cancel
Loading...
Resume bidding, if the page does not update immediately.
Place bid
Review and confirm your bid
Bid confirmation
d
h
m
s
day
hour
hours
FREE postage
See item description
Calculate
(Approximately ##1##)
(Enter ##1## or more)
(Enter more than ##1##)
Your max bid:
Increase max bid
Place bid
Confirm bid
Increase max bid
Cancel
Change bid
Close
, you've been outbid. Don't let it get away - bid again!
, you're the highest bidder on this item. Good luck
, you're the first bidder. Hope you win!
, you're currently the high bidder, but you're close to getting outbid.
, this auction is almost over and you're currently the high bidder.
, you're the high bidder, but the reserve price hasn't been met.
Please enter your bid again.
Please enter a valid number as the bid price.
Enter an amount that is equal or greater than the minimum bid required. This can be found under the bid entry box.
Maximum bids can't be lowered once they're submitted.
This seller requires the buyer to have a PayPal account to purchase this item. Get a PayPal account here .
Your bid is greater than or equal to the Buy It Now price. We recommend you purchase this item via Buy It Now. If you still wish to bid, you may do so below.
Time left:
Current bid:
(approximately ##1##)
Your maximum bid:
(approximately ##1##)
Increase your maximum bid:
By clicking 1 Click Bid, you commit to buy this item from the seller if you're the winning bidder. Learn moreabout 1-click bid - opens in a new window or tab
day
hour
min
sec
days
hours
mins
secs
(approximately ##1##)
Winning bid:
Starting bid:
Close
Congratulations! The auction has ended and you're the winner.
The auction has ended, but the reserve price was not met.
Sorry, the auction has ended and you were outbid.
Good news, you're the high bidder.
Sorry, you've been outbid.
You're the high bidder, but the reserve price is not met.
Please enter a higher amount than the current bid.
Maximum bids cannot be lowered once submitted.
Please enter a valid number.