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About this product
- DescriptionA comprehensive review of the recent developments in DNA repair that have potential for translational and clinical applications. The authors explain in detail the various mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the clinical impact of such vel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK, w under development and close to clinical trials. The book captures-for both cancer researchers and practicing oncologists dealing with hallmark relapse or drug resistance phemena on a daily basis-the many exciting new uses of DNA repair inhibitors, either alone or in combination with anticancer therapies.
- PublisherHumana Press Inc.
- Date of Publication19/03/2004
- SubjectClinical Medicine: Professional
- Series TitleCancer Drug Discovery and Development
- Place of PublicationTotowa, NJ
- Country of PublicationUnited States
- ImprintHumana Press Inc.
- Content Note50 black & white illustrations, biography
- Weight1550 g
- Width155 mm
- Height235 mm
- Spine22 mm
- Edited byLawrence C. Panasci,Moulay A. Alaoui-Jamali
- Format DetailsLaminated cover
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