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- DescriptionThis third edition is comprised of well-established protocols that are considered the gold standard in the field as well as new methodologies for mitochondrial DNA analysis. of Mitochondrial DNA: Methods and Protocols describes protocols for detecting mutations in mitochondrial DNA, techniques to assess mitochondrial DNA damage, visualization of mitochondrial DNA in situ, detection of mitochondrial DNA nucleoids within the mitochondria, methods for analyzing mitochondrial DNA replication, mitochondrial DNA-encoded protein translation and mitochondrial DNA copy number, the latest techlogies for modifying the mitochondrial geme and methods for the purification of proteins involved in the replication and transcription of mitochondrial DNA. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding kwn pitfalls. Authoritative and practical, Mitochondrial DNA: Methods and Protocols, Third Edition will be useful t only for mitochondrial researchers but also for scientists studying human diseases where mitochondrial DNA variation has been recognized as an important pathogenic factor, including cancer and neurodegeneration.
- PublisherHumana Press Inc.
- Date of Publication07/11/2015
- SubjectLife Sciences: General
- Series TitleMethods in Molecular Biology
- Series Part/Volume Number1351
- Place of PublicationTotowa, NJ
- Country of PublicationUnited States
- ImprintHumana Press Inc.
- Content Note10 black & white tables, biography
- Weight726 g
- Width178 mm
- Height254 mm
- Spine20 mm
- Edited byMatthew McKenzie
- Edition Statement3rd Revised edition
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