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- DescriptionProtein misfolding is a key feature of many disorders in humans, given that over twenty proteins are kwn to misfold and cause disease. In Protein Folding, Misfolding, and Disease: Methods and Protocols, experts in the field present a collection of current methods for studying the analysis of protein folding and misfolding, featuring strategies for expressing and refolding recombinant proteins which can then be utilized in subsequent experiments. This detailed volume also covers methods for analyzing the formation of amyloid, protocols for determining the size and structure of native and misfolded proteins, as well as specific examples of where misfolded proteins can be examined using state-of -the-art techlogies. Written in the highly successful Methods in Molecular Biology(t) series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding kwn pitfalls. Up to date and authoritative, Protein Folding, Misfolding, and Disease: Methods and Protocols offers researchers the tools necessary to move ahead in this vital field.
- PublisherHumana Press Inc.
- Date of Publication30/06/2011
- SubjectLife Sciences: General
- Series TitleMethods in Molecular Biology
- Series Part/Volume Number752
- Place of PublicationTotowa, NJ
- Country of PublicationUnited States
- ImprintHumana Press Inc.
- Content Note50 black & white illustrations, 4 black & white tables
- Weight677 g
- Width178 mm
- Height254 mm
- Spine15 mm
- Edited byA.F. Hill,K. Barnham,R. Cappai,S.P. Bottomley
- Format DetailsLaminated cover
- Edition Statement2011
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