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About this product
- DescriptionDrug resistance continues to be a major problem in the effective treatment of many diseases. Resistance to chemotherapy, whether intrinsic or extrinsic, is the result of at least three well defined mechanisms: prevention of the interaction of drug with the target, decreased intracellular concentration of the drug due to an increased efflux or a decreased influx, and enzymatic modification or destruction of the drug. With the advancement in techlogy, the molecular mechanisms of drug resistance have been unravelling at a rapid rate. This book is a timely review of such advances in drug resistance research. The nine chapters of this book, written by a group of clinicians and scientists, elegantly summarises recent advances in our understanding of this important clinical problem with emphasis on cisplatin, fibroblasts, natural compounds, erythropoiesis-stimulating agents, prostate cancer and kidney cancer. This book will be an important contribution to science, and an invaluable tool for researchers who are interested in drug resistance.
- PublisherNova Science Publishers Inc
- Date of Publication01/03/2014
- SubjectMedicine: General
- Place of PublicationNew York
- Country of PublicationUnited States
- ImprintNova Science Publishers Inc
- Content Noteillustrations (black and white, and colour)
- Weight520 g
- Width155 mm
- Height230 mm
- Edited byChristudas Morais
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