Ankylosing Spondylitis (AS) and related diseases called spondyloarthropathies (SpA) are the second most common form of chronic inflammatory arthritis after Rheumatoid Arthritis (RA). Unfortunately, most patients with AS and SpA are either never diagsed or inadequately treated. The current mean delay in the diagsis of AS ranges from 5 to 10 years, and the presenting clinical manifestations of these diseases are wide-ranging and heterogeneous, and thus a variety of health care professionals see AS and SpA patients, from primary care physicians to rheumatologists and other medical and surgical specialists. With the availability of newer, highly effective treatments and better methods of musculoskeletal imaging, such as the MRI, there is an urgent need to improve early diagsis and reduce any inappropriate delay in obtaining effective treatment. Earlier diagsis and treatment can mitigate the severity of the disease, and make a meaningful difference for patient care and quality of life. The proposed book is designed for specialists and generalists alike and intended to help expedite accurate diagses and initiation of appropriate treatment to alleviate unnecessary suffering. Part of the new Oxford American Rheumatology Library series, this pocket-sized book provides practical, evidence-based information for clinicians to aid diagsis, treatment and follow-up care for patients with AS and SpA. The book describes pointers to early diagsis, progsis, clinical manifestations, socioecomic aspects, and disease management. It also provides comprehensive coverage of current treatment options, including the latest biologics, as well as n-drug therapies.