Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Tests for Evaluating Musculoskeletal Complaints in Children: Comparative Effectiveness Review Number 50 by Agency for Healthcare Resea And Quality, U S Department of Heal Human Services (Paperback / softback, 2013)

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Musculoskeletal (MSK) pain is common in children and adolescents, with an estimated prevalence ranging from 2 to 50 percent. MSK pain can affect physical, psychological, and social function and often prompts consultation with a physician.
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