This contemporary book covers significant new kwledge that has emerged during the last two decades and, thus, provides vel antibody phylogenetic perspectives relevant to development of new antibody-based therapeutics and vaccines. It fills a much-needed niche in the area of immuglobulin genetics across species from a comparative perspective. New insights and perspectives from immuglobulin genetics from species such as sea lamprey, cattle, marsupial, bat, rat, rabbit, and swine-other species than the traditional subjects of mice and humans-are relevant to antibody design and engineering. These new perspectives find direct application in the cutting-edge areas of antibody design, engineering and therapeutics, antibody-drug conjugates, and vel antibody-based vaccines. This book fills the need to provide updated kwledge of this newly exploded area that is finding applications in new drug development. No other competing books on the topic are available in the market. The book will be of great interest to immulogists, immulogy researchers, immugeneticists, researchers in pharmaceutical science, those involved in the infectious disease and antibody therapeutics areas, and many others.