Generalized estimating equations have become increasingly popular in biometrical, ecometrical, and psychometrical applications because they overcome the classical assumptions of statistics, i.e. independence and rmality, which are too restrictive for many problems. Therefore, the main goal of this book is to give a systematic presentation of the original generalized estimating equations (GEE) and some of its further developments. Subsequently, the emphasis is put on the unification of various GEE approaches. This is done by the use of two different estimation techniques, the pseudo maximum likelihood (PML) method and the generalized method of moments (GMM). The author details the statistical foundation of the GEE approach using more general estimation techniques. The book could therefore be used as basis for a course to graduate students in statistics, biostatistics, or ecometrics, and will be useful to practitioners in the same fields.
After studying statistics and mathematics at the University of Munich, Andreas Ziegler obtained his doctoral degree from the University of Dortmund (Germany) for his thesis on methodological developments on generalized estimating equations. In the past 15 years, he has authored or co-authored more than 300 journal articles and 6 books. He has received several awards for his methodological developments and collaborative studies in clinical trials and genetic epidemiology. Andreas Ziegler is professor and head of the Institute of Medical Biometry and Statistics at the University of Lubeck (Germany).