The lowest-priced brand-new, unused, unopened, undamaged item in its original packaging (where packaging is applicable).Packaging should be the same as what is found in a retail store, unless the item is handmade or was packaged by the manufacturer in non-retail packaging, such as an unprinted box or plastic bag.See details for additional description.
Your geme is an email attachment What a difference a few years can make? In 2001, to a global fanfare, the completion of the frst draft sequence of the human geme was anunced. This had been a Herculean effort, involving thousands of researchers and millions of dollars. Today, a project to re-sequence 1,000 gemes is well underway, and within a year or two, your own personal geme is likely to be available for a few thousand pounds, a price that will undoubtedly decrease further. We are fast approaching the day when your geme will be available as an email attachment (about 4 Mb). The key to this feat is the fact that any two human gemes are more than 99% identical, so rather than representing every base, there is really only a requirement to store the 1% of variable sequence judged against a common reference geme. This brings us directly to the focus of this edition of Methods in Molecular Biology, Genetic Variation. The human geme was once the focus of biology, but w individual geme var- tion is taking the center stage. This new focus on individual variation ultimately democ- tizes biology, offering individuals insight into their own phetype. But these advances also raise huge concerns of data misuse, misinterpretation, and misunderstanding. The immediacy of individual gemes also serves to highlight our relative igrance of human genetic variation, underlining the need for more studies of the nature and impact of genetic variation on human phetypes.