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In the first handbook to comprehensively cover the emerging area of systems toxicology, the Handbook of Systems Toxicology provides an authoritative compilation of up-to-date developments presented by internationally recognised investigators. Focusing on two rapidly developing cutting edge techlogies - omics techlogy and natechlogy with special emphasis on their applications - the scope and structure reflects the multidimensional character of these areas of toxicological research. Cutting edge molecular techlogies such as microarray, proteomics, metabolomics, informatics, biomarkers, in vivo and in vitro models as well as the use of these new techlogies in regulatory environments are addressed. An insight into the current trends and future directions of research in this rapidly developing field is also provided, offering an excellent source of authoritative and up-to-date information for investigators, toxicologists, risk assessors and regulators in academia, industry and government. New online resource available w! In 2011, the content from the Handbook of Systems Toxicology merged with the third edition of the six-volume General and Applied Toxicology. The result? General, Applied and Systems Toxicology - a new online resource combining traditional toxicology with the latest developments to present the ultimate reference in toxicology! For full details visit wileyonlinelibrary.com/ref/gast