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About this product
- DescriptionHCC is the most common primary cancer of the liver and according to the WHO report, the fourth commonest cause of death. The estimated incidence of new cases worldwide is about 500,000-1,000,000 per year causing 600,000 deaths globally per year. Although there are large areas of the world where the incidence of HCC is still unkwn, several countries in East Asia and some Sub-Saharan African regions are affected by a very high prevalence of HCC (over 20 cases/100,000 population). Areas with a moderately high risk (11-20 cases/100,000 population) include Italy, Spain and Latin America, while France, Germany and the United Kingdom have instead an intermediate risk (5-10 cases/100,000 population). A relatively low prevalence (less than 5 cases/100,000 population) is found in the United States, Canada and Scandinavia. The incidence of HCC has been rising in developed western countries in the last two decades, along with the emergence of the hepatitis C virus infection and due to the rise of immigration rates from HBV-endemic countries. In addition, even though the incidence of HCC reaches its highest peak among persons over 65 years, an increased incidence among younger individuals has been ted in the last two decades both in USA and Europe. A multidisciplinary approach should be taken when assessing patients with HCC; stage of HCC and liver disease should always be taken into account and the best treatment should be offered. Liver resection and ablative treatments should never be denied to patients, and curative procedures should be performed in hepato-biliary-pancreatic centers. Each HCC patient has to be evaluated singularly, stratifying each time the risk for the procedure so as to determine which treatment is the best treatment. It is also important to analyse all the possibilities that can be offered. This similar approach showed a good efficacy and safety in all frail patient categories, such as elderly patients or patients with HCC and HIV infection. Early diagsis of HCC and retreatment for HCC recurrence have a key role in the survival of patients. Therefore, regular screening programs for HCC should be extended to all patients according to proposed guidelines, together with a greater proclivity for treatment and retreatment options in cases of an HCC diagsis or recurrence. This may be an important and needed breakthrough for this rising problem.
- Author BiographyDr Massimiliano Berretta, born in 1972 graduated from Medical School at the University of Catania, Italy, in 1996. He achieved his Specialty Degree in Oncology in 2001, and in Geriatrics and Gerontology in 2009, at the same University. He works as assistant at the Division of Medical Oncology A, Department of Medical Oncology, National Cancer Institute of Aviano since 2004. Since October 2005 is a visiting professor at the PhD in multimodal approach oncology geriatric at the University of Catania. Since November 2013 he is a member of the Euro-Mediterranean Institute of Science and Technology (IEMEST), Palermo; From May 2011 he joined the Board of Directors of Multidisciplinary Studies in Oncology (ASMO); From March 2009, he is a member of the Italian Association of Thoracic Oncology (AIOT); From January 2008 he is member of the Italian Germ Cell Cancer Group (IGG); From April 2006 is member of the Italian Association of Medical Oncology (AIOM); From January 2006 he is member of the American Society of Clinical Oncology (ASCO); Since November 2002 he is member of the Italian Cooperative Group Aids and Cancer (Gicat); Since October 1999 he is a member of the Italian Sarcoma Group.
- PublisherNova Science Publishers Inc
- Date of Publication01/01/2016
- SubjectClinical Medicine: Professional
- Place of PublicationNew York
- Country of PublicationUnited States
- ImprintNova Science Publishers Inc
- Content Noteillustrations
- Weight578 g
- Width180 mm
- Height260 mm
- Edited byBruno Cacopardo,Massimiliano Berretta
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