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About this product
- DescriptionIndoles continue to be of great interest to the pharmaceutical industry and at the current time several thousand specific new derivatives are reported annually. Research has been driven by the wide range of indole derivatives which occur in nature and through the biological activity of many indole derivatives, of both natural and synthetic origin.This book provides a systematic guide to the most useful and important reactions in the field for both synthesis and synthetic modification of the indole ring. While including the most recently developed and promising methods, it also updates informationavailable on classical methods to give the reader an up-to-date and comprehensive view of the subject. The methods are illustrated by procedures drawn from the literature and by tables including examples chosen to indicate both the scope of applicabilityand variations in methodology. The organization of the book is based on the retrosynthetic concept of identifying the bond(s) formed in the reaction, which in turn identifies potential starting materials.
- Author BiographyRichard J. Sundberg has been a member of the chemistry department at the University of Virginia since 1964. His research has included both development of synthetic methods for indoles and other heterocycles. The scope of his research also extends into the synthesis of biologically active compounds, including natural products such as the vinca alkaloids. Alan Katritzky, educated at Oxford, held faculty positions at Cambridge and East Anglia before migrating in 1980 to the University of Florida, where he is Kenan Professor and Director for the Institute for Heterocyclic Compounds. He has trained more than 1000 graduate students and post-docs, and lectured and consulted world-wide. He led the team, which produced Comprehensive Heterocyclic Chemistry and its sequels, CHEC-II and CHEC-III , has edited Advances in Heterocyclic Chemistry, Vols. 1 through 100 and conceived the plan for Comprehensive Organic Functional Group Transformations . He founded Arkat-USA, a non-profit which publishes Archive for Organic Chemistry (ARKIVOC) electronic journal completely free to authors and readers at (www.arkat-usa.org). Honors include 14 honorary doctorates from 11 countries and membership or foreign membership of the National Academies of Britain, Catalonia, India, Poland, Russia and Slovenia.
- Author(s)Richard J. Sundberg
- PublisherElsevier Science Publishing Co Inc
- Date of Publication28/05/1996
- Series TitleBest Synthetic Methods
- Place of PublicationSan Diego
- Country of PublicationUnited States
- ImprintAcademic Press Inc
- Weight400 g
- Width152 mm
- Height229 mm
- Series Edited byAlan R. Katritzky,O. Meth-Cohn,C.S. Rees
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