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About this product
- DescriptionKwledge about cancer genetics is rapidly expanding, and has implications for all aspects of cancer research and treatment, including molecular causation, diagsis, prevention, screening, and treatment. Additionally, while cancer genetics has traditionally focused on mutational events that have their primary effect within the cancer cell, recently the focus has widened, with evidence of the importance of epigenetic events and of cellular interactions in cancer development. The role of common genetic variation in determining the range of individual susceptibility within the population is increasingly recognized, and is w being widely addressed using information from the Human Geme Project. These new research directions will highlight determinants of cancer that lie outside the cancer cell, suggest new targets for intervention, and inform the design of strategies for prevention in groups at increased risk. Today, the NCI is putting more and more money into research into the genetics of cancer. The very first of the NCI's stated research priorities is a project called The Cancer Geme Atlas. The Cancer Geme Atlas (TCGA) is a comprehensive and coordinated effort to accelerate the understanding of the molecular basis of cancer through the application of geme analysis techlogies, including large-scale geme sequencing. The NCI and the NHGRI (National Human Geme Research Institute, where the series editor is employed) have each committed $50 million over three years to the TCGA Pilot Project. This book proposes cover the latest findings in the genetics of male reproductive cancers; specifically cancers of the prostate and testes. The volume will cover the epidemiology of these cancers; model systems, pathology, molecular genetics, and inherited susceptibility.
- PublisherSpringer-Verlag New York Inc.
- Date of Publication03/05/2012
- SubjectClinical Medicine: Professional
- Series TitleCancer Genetics
- Place of PublicationNew York, NY
- Country of PublicationUnited States
- ImprintSpringer-Verlag New York Inc.
- Content Note18 black & white illustrations, 5 colour illustrations, 9 black & white tables, biography
- Weight551 g
- Width155 mm
- Height235 mm
- Spine19 mm
- Edited byKathleen A. Cooney,William D. Foulkes
- Edition StatementPreviously published in hardcover
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