Scientists can use molecular profiling microarrays to compare healthy cells with their diseased counterparts and develop gene-specific treatments. Finding the best way to interpret original profiling data into accurate trends, however, continues to drive the development of normalization algorithms and software tools. Methods in Microarray Normalization compiles the most useful and novel techniques for the first time into a single, organized source. Experts in the field provide a diverse view of the mathematical processes that are important in normalizing data and avoiding inherent systematic biases. They also review useful software, including discussions on key algorithms, comparative data, and download locations. The book discusses the use of early normalization techniques for new profiling methods and includes strategies for assessing the utility of various normalization algorithms. It presents the latest microarray innovations from companies such as Agilent, Affymetrix, and GeneGo as well as new normalization methods for protein and CGH arrays, many of which are applicable for antibody, microRNA, methylation, and siRNA arrays. Methods in Microarray Normalization provides scientists with a complete resource on the most effective tools available for maximizing microarray data in biochemical research. Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.
Product Identifiers
Publisher
Taylor & Francis Inc
ISBN-13
9781420052787
eBay Product ID (ePID)
95252089
Product Key Features
Author
Phillip Stafford
Publication Name
Methods in Microarray Normalization
Format
Hardcover
Language
English
Subject
Biology
Publication Year
2008
Type
Textbook
Number of Pages
320 Pages
Dimensions
Item Height
234mm
Item Width
156mm
Volume
10
Item Weight
590g
Additional Product Features
Series Title
Drug Discovery Series
Country/Region of Manufacture
United States
Editor
Phillip Stafford
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