All listings for this product
Best-selling in Textbooks
Save on Textbooks
- AU $8.59Trending at AU $13.93
- AU $69.88Trending at AU $71.38
- AU $14.50Trending at AU $15.71
- AU $15.52Trending at AU $23.29
- AU $32.75Trending at AU $55.26
- AU $91.99Trending at AU $99.52
- AU $30.02Trending at AU $32.01
About this product
- DescriptionEmphasizing their emerging capabilities, this volume provides a strong foundation for an understanding of how micro- and natechlogies used in biomedical research have evolved from concepts to working platforms. Volume editor Christopher Love has assembled here a highly interdisciplinary group of authors with backgrounds ranging from chemical engineering right up to materials science to reflect how the intersection of ideas from biology with engineering disciplines has spurred on invations. In fact, a number of the basic techlogies described are reaching the market to advance the discovery and development of biopharmaceuticals. The first part of the book focuses on microsystems for single-cell analysis, examining tools and techniques used to isolate cells from a range of biological samples, while the second part is dedicated to tiny techlogies for modulating biological systems at the scale of individual cells, tissues or whole organisms. New tools are described which have a great potential for (pre)clinical development of interventions in a range of illnesses, such as cancer and neurological diseases. Besides describing the promising applications, the authors also highlight the ongoing challenges and opportunities in the field.
- Author BiographyJ Christopher Love: Education: Ph.D., Harvard University, 2004 B.S., University of Virginia, 1999 Now at Massachusetts Institute of Technology Department of Chemical Engineering Honors and Awards Camille Dreyfus Teacher-Scholar Award, 2012 Two NIH Single-Cell Analysis Program awards, 2012 Popular Science's 'Brilliant 10, 2010 W.M. Keck Distinguished Young Scholar for Medical Research, 2009 Dana Scholar for Human Immunology, 2009 Life Sciences Research Foundation Postdoc Fellow (Gilead Sciences), 2004 Foresight Distinguished Student Award in Nanotechnology, 2000 Natl. Defense Science and Engineering Graduate Fellow, 1999-2002 Barry S. Goldwater Scholarship, 1998 Phi Beta Kappa, 1998 The Love Lab is exploring the heterogeneity present in populations of cells and characterizing the dynamic biological responses of individual cells subjected to defined perturbations. We develop new processes for analyzing large numbers of individual living cells quantitatively and dynamically. The primary approach uses simple technologies, based on soft lithography or unconventional nanofabrication, to measure multiple characteristics of single cells, and from those data, we aim to construct detailed profiles that describe the state and evolution of the cell itself or the multicellular population of which it is a member. The applications for these technologies that we are pursuing include clonal selection for bioprocess manufacturing, discovery of new immunotherapies, and immunological monitoring for diagnosis and biomedical research in clinical immunology. The lab itself is an interdisciplinary and team-oriented environment. We apply concepts and techniques from surface chemistry, materials science, physics, and chemical engineering to address biological questions in immunology, microbiology, systems biology, and bioprocess engineering. Particular areas of emphasis in clinical immunology presently are infectious diseases and autoimmune disorders. We value expertise from a range of backgrounds relevant to these areas of research. The long-term objectives of our work are to understand how heterogeneity in populations of cells affects their collective behaviors as a system, and to gain insights into the biological variations present in unique and rare cells from those populations. We also aim to facilitate the transfer of these technologies into clinical laboratories for extended use in biomedical research.
- Author(s)J Christopher Love
- PublisherWiley-VCH Verlag GmbH
- Date of Publication07/04/2016
- SubjectLife Sciences: General
- Series TitleAdvanced Biotechnology
- Place of PublicationWeinheim
- Country of PublicationGermany
- ImprintWiley-VCH Verlag GmbH
- Weight808 g
- Width175 mm
- Height245 mm
- Spine20 mm
This item doesn't belong on this page.
Thanks, we'll look into this.