Environmental ise is a threat to public health, having negative impacts on human health and wellbeing. This book reviews the health effects of night time ise exposure, examines dose-effects relations, and presents interim and ultimate guideline values of night ise exposure.It offers guidance to the policy-makers in reducing the health impacts of night ise, based on expert evaluation of scientific evidence in Europe. The review of scientific evidence and the derivation of guideline values were conducted by outstanding scientists. The contents of the document were peer-reviewed and discussed for a consensus among the experts and the stakeholders. We are thankful for those who contributed to the development and presentation of this guidelines and believe that this work will contribute to improving the health of the people in the Region.