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When Ham III, the grandson of the Space Agencys legendary chimpanzee astronaut is recruited to help retrieve a lost space probe, he has a close encounter of the hilarious kind as he teams up with the lovely Lieutenant Luna and their by-the-book commander, Titan. But when the ship crash-lands on a strange planet, can this mismatched chimp crew work together to save the mission without driving each other bananas?
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Andy Samberg, Carlos Alazraqui, Cheryl Hines, Jane Lynch, Jason Harris, Jeff Daniels, Jessica Gee, Kath Soucie, Kenan Thompson, Kristin Chenoweth, Lloyd Jay Keiser, Omid Abtahi, Patrick Breen, Patrick Warburton, Stanley Tucci, Tom Kenny, Wally Wingert, Zack Shada