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About this product
- DescriptionSuccessful drug use in biology and medicine is often prejudiced by the failure of drugs that are otherwise active in vitro to act as efficiently in vivo. This is because in the living animal drugs must, as a rule, bypass or traverse organs, membranes, cells and molecules that stand between the site of administration and the site of action. In practice, however, drugs can be toxic to rmal tissues, have limited or access to the target and be prematurely excreted or inactivated. There is w growing optimism that such problems may be resolved by the use of carrier systems that will t only protect the n-target environment from the drugs they carry but also deliver them to where they are needed or facilitate their release there. Carrier systems presently under investigation include antibodies, glycoproteins, cells, reconstituted viruses and liposomes. Recent advances in the chemistry of cell receptor and receptor-recognising molecules, llnmulogy, and natural and artificial membranes have revealed a multitude of ways in which such carrier systems can be modified or improved upon.
- PublisherSpringer-Verlag New York Inc.
- Date of Publication01/09/1982
- SubjectCoping with Problems & Illness
- Series TitleNATO Science Series A
- Series Part/Volume Number47
- Place of PublicationNew York, NY
- Country of PublicationUnited States
- ImprintSpringer-Verlag New York Inc.
- Content Notebiography
- Weight760 g
- Width170 mm
- Height244 mm
- Spine22 mm
- Edited byGregory Gregoriadis
- Format DetailsTrade paperback (US)
- Edition StatementSoftcover reprint of the original 1st ed. 1982
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