Indian immigrant Tilo (Aishwarya Rai) runs Spice Bazaar, a spice shop in Oakland, California. With the guidance of her spices, she finds the perfect remedy for anyone who walks through her door. For her powers to work, she must obey three simple but strict rules - she must only use the spices to help others, she must not touch another human's skin and she must never leave her store. When hunky American Doug (Dylan McDermott) ventures into Tilo's establishment, he unlocks her forbidden passions, which threaten to destroy her 'spice-girl' powers. Tilo must now confront her past, her friends, her desires and ultimately the spices to decide if she can fight for a new life of her choosing or must return to the old one.