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About this product
- DescriptionIt is w just 20 years since Gomatos and his co-workers at the Rocke- feller University showed that the nucleic acid in reovirus particles is double-stranded RNA (dsRNA). This discovery created great excitement, for dsRNA was at that time under intense investigation as the replicative form of viral gemes consisting of single-stranded RNA. An equally interesting and important finding followed soon after: it was found that the reovirus geme consists, t of a single nucleic acid molecule, but of 10 discrete segments, each with its specific sequence content and each transcribed into its own messenger RNA. It is clear w that these segments are genes. Not surprisingly, the availability of a viral geme 10 unlinked genes has permitted some unique lines of in- consisting of vestigation in molecular biology. Mammalian and avian reoviruses proved to be but the first of several viruses recognized as sharing Similarity in size and morphology and ge- mes consisting of 10, II, or 12 separate genes. These viruses are dis- tributed throughout living organisms; among the natural hosts of mem- bers of this virus family are vertebrates, Insects, and plants. Members of the Reoviridae family differ widely in the virulence that they exhibit toward their hosts . . For example, the first discovered mam- malian reovirus literally is, as the name signifies, a respiratory enteric orphan virus, that is, a virus unassociated with disease.
- PublisherSpringer-Verlag New York Inc.
- Date of Publication31/05/2013
- SubjectClinical Medicine: Professional
- Series TitleThe Viruses
- Place of PublicationNew York
- Country of PublicationUnited States
- ImprintSpringer-Verlag New York Inc.
- Content Notebiography
- Weight814 g
- Width156 mm
- Height234 mm
- Spine30 mm
- Edited byWolfgang K. Joklik
- Format DetailsTrade paperback (US)
- Edition StatementSoftcover reprint of the original 1st ed. 1983
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