Imaging of the Dopaminergic system in the human brain with the in vivo use of Positron Emis- sion Tomography has emerged in the late 1980s as a tool of major importance in Clinical Neuros- ciences and Pharmacology. The last few years have witnessed the rapid development of new radiotracers specific to receptors, reuptake sites and enzymes of the dopamine system; the application of these radiotracers has led to major breakthroughs in the pathophysiology and therapy of movement disorders and schizophrenic-like psychoses. This book is the first to collect, in a single volume, state-of-the-art contributions to the various aspects of this research. Its contents address methodological issues related to the design, labelling, quantitative imaging and compartmental modelisation of radioligands of the post-synaptic, pre-synaptic and enzyme sites of the dopamine system and to their use in clinical research in the fields of Parkinson's disease as well as other movement disorders, psychoses and neuroleptic receptor occupancy. The chapters were written by leading European scientists in the field of Positron Emission Tomography, gathered together in Caen (France, November 1990) under the aegis of the EEC Concerted Action on PET Investigations of Cellular Regeneration and Degeneration. This book provides a current and comprehensive overview on PET studies of the brain dopamine system which should aid and interest neurologists, psychiatrists, pharmacologists and medical imaging scientists. J. C. Baron D. Comar L. Farde J. L. Martit B. Mazoyer August 1991 ix LIST OF CONTRffiUTORS Dr Yves Agid DrL.
Product Identifiers
Publisher
Springer
ISBN-10
9401055610
ISBN-13
9789401055611
eBay Product ID (ePID)
148733118
Product Key Features
Format
Paperback
Language
English
Subject
Clinical Medicine: Professional
Dimensions
Weight
338g
Height
235mm
Width
155mm
Additional Product Features
Place of Publication
Dordrecht
Spine
12mm
Edited by
D. Comar, L. Farde, B.M. Mazoyer, J.L. Martinot, J.C. Baron