In Crash Bandicoot: Fusion and Spyro: Fusion, Dr. Neo Cortex (Crash's nemesis) and Ripto (Spyro's nemesis) have accidentally met up through underground portals and are set on taking over the entire universe. In an attempt to share resources and expand their territories, Cortex and Ripto are using portals to flood their two worlds with their evil minions. Crash and Spyro must team up with each other to discover the identity of the new menace and save the universe from this evil plot!