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Cardiotoxicity of Non-Cardiovascular Drugs by Giorgio Minotti (Hardcover, 2010)

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Some drugs which are not aimed at treating heart disease have nevertheless been found to have profound effects on heart muscle. Cardiotoxicity is one of the major forms of toxicity seen in drugs and it accounts for most drug recalls and delays experienced in regulatory approvals.In recent years a number of non-cardiac blockbuster drugs such as terfenadine have been withdrawn from major markets because of cardiotoxicity concerns, while other drugs have either been withdrawn prior to marketing or required labelling changes that significantly restricted their use. In Cardiotoxicity of Non-Cardiovascular Drugs international experts describe the molecular mechanisms and clinical read-outs of cardiac events induced by a broad variety of noncardiovascular drugs. Particular emphasis is paid to the preclinical screening of drug cardiotoxicity. Topics include: metabolic targets of cardiotoxicity regulatory aspects translating molecular mechanisms into clinical trials structure-activity relationships in arrhythmias by antihistamines and psychoactive drugs cardiovascular toxicity of antitumor drugs cardiovascular toxicities of non-steroidal anti-inflammatory drugs cardiovascular toxicities of antiretroviral therapies Cardiotoxicity of Non-Cardiovascular Drugs is an essential guide to this important area of drug development. It will find a place on the bookshelves of researchers, regulators and students in medicinal chemistry, drug development, pharmacology, pharmacy and cardiovascular disease.

Product Identifiers

Publisher
John Wiley & Sons Inc
ISBN-13
9780470772744
eBay Product ID (ePID)
92565197

Product Key Features

Author
Giorgio Minotti
Publication Name
Cardiotoxicity of Non-Cardiovascular Drugs
Format
Hardcover
Language
English
Subject
Medicine
Publication Year
2010
Type
Textbook
Number of Pages
360 Pages

Dimensions

Item Height
235mm
Item Width
162mm
Item Weight
650g

Additional Product Features

Title_Author
Giorgio Minotti
Country/Region of Manufacture
United States

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Cardiotoxicity of Non-Cardiovascular Drugs by Giorgio Minotti (Hardcover, 2010)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

Best Selling in School Textbooks & Study Guides

Tracks, Scats and Other Traces: Reissue by Barbara Triggs (Paperback, 2004)

Self-Made Man: My Year Disguised as a Man by Norah Vincent (Paperback, 2006)

Save on School Textbooks & Study Guides

Powerless: Tiktok Made Me Buy It! an Epic and Sizzling Fantasy Romance Not to Be

Viktor Schauberger The Water Wizard (Paperback)

Targeting Mental Maths Australian Curriculum Year 5 - New Edition 2023

The MeatEater Fish and Game Cookbook Recipes and Techniques for Every Hunter and

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