Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are just as important but have been largely ignored in other works. They are causative agents for diseases including hypertension, diabetes, heart disease, and arthritis so offer new, and often more approachable, targets for drug design. Aimed at medical professionals and pharmaceutical specialists, this book integrates extracellular and intracellular signalling processes and offers a fresh perspective on new drug targets. Written by colleagues at the same institution, but with contributions from leading international authorities, it is the result of close cooperation between the authors of different chapters. Readers are introduced to a new approach to disease causation by adipokines and toxic lipids. Heart disease, migraines, stroke, Alzheimer's disease, diabetes, cancer, and arthritis are approached from the perspective of prevention and treatment by alteration of extracellular signalling. Evidence is presented that the avoidance of toxic lifestyles can reduce the incidence of such illnesses and new therapeutic targets involving adipokines, ceramide and endocannabinoids are discussed.
Product Identifiers
Publisher
Royal Society of Chemistry
ISBN-13
9781849731607
eBay Product ID (ePID)
109263150
Product Key Features
Author
James D Adams, Keith Parker
Publication Name
Extracellular and Intracellular Signaling
Format
Hardcover
Language
English
Subject
Chemistry, Psychiatry
Publication Year
2011
Type
Textbook
Number of Pages
303 Pages
Dimensions
Item Height
234mm
Item Width
156mm
Volume
Volume 10
Item Weight
604g
Additional Product Features
Series Title
Drug Discovery
Editor
James D Adams, Keith Parker
Country/Region of Manufacture
United Kingdom
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