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Guide to Mutation Detection by Human Genome Organization (HUGO) (Paperback, 2005)

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Product Information

As genomic science and potential gene therapies continue to develop, the detection of mutations plays an increasingly central role in diverse areas of biology. With innumerable detection techniques available spanning multiple disciplines, the choice of the best method for a particular study can prove exceedingly difficult. Complexity, equipment requirements, cost, and throughput are all factors to consider, along with the huge amount of information already available through genome sequencing projects. An essential go-to for informed decision-making, the Guide to Mutation Detection is the only single source for the theory and practice of mutation analysis needed to design an experiment. User-friendly, concise, and expertly edited by recognized leaders in the field, the text provides a cutting-edge reference that is still accessible to those with no experience in mutation analysis. The coverage is divided into two sections, with the first section reviewing such topics as: * Key technologies * Mutation scanning * Cleavage * Quality control * High throughput approaches * Databases * Nomenclatures The second section focuses on step-by-step protocols and discussion of methods, including: * Tag-array minisequencing * Electronic hybridization * Pyrosequencing * Fluorescent Single-Stranded Conformation Polymorphism (SSCP) * Denaturing High-Performance Liquid Chromatography (DHPLC) * Array Comparative Genomic Hybridization (ACGH) * Microplate Array Diagonal Gel Electrophoresis (MADGE) Throughout the text, the emphasis remains on practical applications. The detailedprotocols derive from the well-regarded Human Genome Organization (HUGO) training course, particularly those in Montpellier, France, 2002, organized by Mirielle Claustres, Johan den Dunnen, and Graham Taylor. Useful appendices contain important safety data, supplier lists, and bioinformatics resources. Up-to-date, user friendly, and comprehensive, the Guide to Mutation Detection is an invaluable resource for students and practitioners working across a wide range of genetics-related disciplines.

Product Identifiers

Publisher
John Wiley & Sons Inc
ISBN-13
9780471234449
eBay Product ID (ePID)
95775929

Product Key Features

Author
Human Genome Organization (Hugo)
Publication Name
Guide to Mutation Detection
Format
Paperback
Language
English
Subject
Biology
Publication Year
2005
Type
Textbook
Number of Pages
330 Pages

Dimensions

Item Height
254mm
Item Width
186mm
Item Weight
614g

Additional Product Features

Title_Author
Human Genome Organization (Hugo)
Country/Region of Manufacture
United States
Editor
Graham R. Taylor, Ian N. Day

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Guide to Mutation Detection by Human Genome Organization (HUGO) (Paperback, 2005)

About this product

Product Information

Product Identifiers

Product Key Features

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Additional Product Features

Best Selling in Adult Learning & University

Permaculture: A Designer's Manual by Bill Mollison (Hardcover, 1988)

Australian Native Bee Book: Keeping Stingless Bee Hives for Pets, Pollination and Sugarbag Honey by Tim Heard (Paperback, 2015)

The Weed Forager's Handbook: A Guide to Edible and Medicinal Weeds in Australia by Adam Grubb, Annie Raser-Rowland (2012, Paperback)

In-Basket Case Studies by Guy Adamson (Paperback, 1986)

Empire of the Summer Moon: Quanah Parker and the Rise and Fall of the Comanches, the Most Powerful Indian Tribe in American History by S.C. Gwynne (Paperback, 2011)

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Netter Atlas of Human Anatomy: Classic Regional Approach

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