The Boov are searching for a new planet to call home. They find the perfect planet in the middle of nowhere - Earth! The Boov kindly relocate all the humans to Happy Humanstown, and then proceed to completely rearrange the planet! By accidentally telling the Boov's worst enemy where they are, Oh becomes the number one Boov fugitive. Oh meets Tip, the only human left in Boston, and their hilarious journey to friendship begins.