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Life-Span Extension: Single-Cell Organisms to Man by Humana Press Inc. (Paperback, 2012)

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Product Information

In recent years, remarkable discoveries have been made concerning the underlying mechanisms of aging. In Life-Span Extension: Single-Cell Organisms to Man, the editors bring together a range of illuminating perspectives from researchers investigating the aging process in a variety of species. This vel work addresses the aging process in species ranging from yeast to man and, among other subjects, features detailed discussions of the naked mole-rat, an exceptionally long-lived rodent; the relationship between dietary factors/food restriction and aging; and an evolutionary view of the human aging process. Single mutations that extend life span have been identified in yeast, worms, flies, and mice, whereas studies in humans have identified potentially important markers for successful aging. At the same time, it has been discovered that the genes and pathways identified in these studies involve a surprisingly small set of conserved functions, most of which have been the focus of aging research for some time. For example, the mTOR pathway, a regulator of translation and protein synthesis, has been identified as a common longevity pathway in yeast and Caerhabditis elegans. In mammals, this pathway intersects with neuroendocrine pathways and with the insulin/insulin-like growth factor pathways, which have been identified as major modulators of life span and aging in both invertebrates and mice. Novel, emerging techlogies and the increasingly wide variety of systems that are w used to study aging and the mechanisms of aging provide ermous opportunities for the identification of common pathways that modulate longevity. It is these common pathways that are the focus of this important volume.

Product Identifiers

Publisher
Humana Press Inc.
ISBN-10
1617797472
ISBN-13
9781617797477
eBay Product ID (ePID)
140030450

Product Key Features

Format
Paperback
Language
English
Subject
Clinical Medicine: Professional

Dimensions

Weight
338g
Height
235mm
Width
155mm

Additional Product Features

Place of Publication
Totowa, NJ
Spine
12mm
Edited by
Holly M. Brown-Borg, Antonello Lorenzini, Christian Sell
Series Title
Aging Medicine
Content Note
20 Black & White Illustrations, 5 Colour Illustrations, 5 Black & White Tables, Biography
Date of Publication
25/02/2012
Country of Publication
United States
Genre
Clinical Medicine: Professional

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Life-Span Extension: Single-Cell Organisms to Man by Humana Press Inc. (Paperback, 2012)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

Best Selling in Adult Learning & University

Australian Guidebook for Structural Engineers by Lonnie Pack (Paperback, 2019)

Eduqas GCSE (9-1) Religious Studies Route B: Catholic Christianity and Judaism by Deirdre Cleary, Andrew Barron, Joy White, Patrick Harrison (Paperback, 2017)

Time Management by Peter Quarry (Paperback, 1986)

The Ethnic Cleansing of Palestine by Ilan Pappe (Paperback, 2007)

Save on Adult Learning & University

The Australian Native Bee Hive Book: Keeping Stingless Sugarbag OATH Tim Heard

Weed Forager's Handbook: A Guide to Edible and Medicinal Weeds in Australia by A

Netter Atlas of Human Anatomy: Classic Regional Approach

The Indoctrinated Brain: How to Successfully Fend Off the Global Attack on Your

Tuning the A-Series Engine: the Definitive Manual on tuning for Performance or E

Classical Mechanics: The Theoretical Minimum by George Hrabovsky

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