Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis. With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include: Electron transport and energy production Mitochondrial biogenesis and dynamics Mitochondrial signaling Apoptosis and autophagy Pharmacology signaling Epigenetic signaling: mitochondrial methylation and acetylation reactions An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.
Product Identifiers
Publisher
Taylor & Francis Inc
ISBN-13
9781439880029
eBay Product ID (ePID)
114081415
Product Key Features
Author
Enrique Cadenas, Lester Packer, Sten Orrenius
Publication Name
Mitochondrial Signaling in Health and Disease
Format
Hardcover
Language
English
Subject
Science, Biology
Publication Year
2012
Type
Textbook
Number of Pages
530 Pages
Dimensions
Item Height
234mm
Item Width
156mm
Item Weight
862g
Additional Product Features
Series Title
Oxidative Stress and Disease
Country/Region of Manufacture
United States
Editor
Lester Packer, Enrique Cadenas, Sten Orrenius
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