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Regulatory T Cells and Interleukin-10 by Marwa Nasser, Nehal Draz, Rasha Nasr (Paperback, 2011)

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About this product

Product Information

Mycobacterium tuberculosis infects one-third of the world's population and causes almost 2 million deaths per year. In spite of intense research on the immune response elicited during tuberculosis, the mechanisms involved in the development of active disease remain obscure. There is growing evidence that regulatory T cells may play an important role in the regulation of host immune responses against M. tuberculosis. In some circumstances, the regulation exerted by regulatory T cells is excessive and prevents the establishment of protective immune responses, whereas in other circumstances, this control is not sufficient to prevent immunopathology. IL-10 has been described as a T helper 2 cytokine with immunosuppressive properties. In addition, IL-10 secretion has been reported as one of the mechanisms by which regulatory T cells may exert their suppressive function. This study, therefore, was conducted to determine CD4+CD25+ regulatory T cells % and the levels of IL-10 mRNA expression in peripheral blood of patients with active pulmonary tuberculosis. This should help to assess a possible role of these cells in the immunopathogenesis of TB, and should be especially useful to researc

Product Identifiers

Publisher
Lap Lambert Academic Publishing
ISBN-13
9783845404370
eBay Product ID (ePID)
109279118

Product Key Features

Author
Marwa Nasser, Nehal Draz, Rasha Nasr
Publication Name
Regulatory T Cells and Interleukin-10
Format
Paperback
Language
English
Subject
Medicine
Publication Year
2011
Type
Textbook
Number of Pages
112 Pages

Dimensions

Item Height
229mm
Item Width
152mm
Item Weight
177g

Additional Product Features

Title_Author
Rasha Nasr, Marwa Nasser, Nehal Draz
Country/Region of Manufacture
Germany

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