As young people, we all question the reason for our existence. When a young nurse named Amanda is present at the birth of James (Jamie) Harrington Jane and she gets to hold the baby, she feels a connection like she has never felt to anyone before. Growing up, Jamie seems destined to have an Amanda in his life, but it does t always bring him happiness. Through his liaisons with various Amandas, he experiences love, joy, and also loss. Amanda's repeated attraction to Jamie takes her on a treacherous road toward her ultimate destiny.