CURRENTLY SOLD OUT

The Renin-Angiotensin System and the Kidney: New Insights and Perspectives by Xiao C. Li, Jia L. Zhuo (Paperback, 2015)

About this product

Product Information

The renin-angiotensin system (RAS) is one of the most important endocrine (tissue-to-tissue), paracrine (cell-to-cell) and intracrine (intracellular/nuclear) humoral systems in the regulation of blood pressure, cardiovascular, and kidney function in health and disease. The RAS has remarkably evolved from the initial discovery of the rate-limiting enzyme renin to a complex biochemical and physiological cascade involving more than a dozen members. Currently, there are up to five axes or pathways identified in the RAS; each has its substrate, enzyme, effector peptide, receptor, and downstream signaling pathways. These include the renin/ACE/ANG II/AT1 receptor, the APA/ANG III/AT2 receptor, the ACE2/ANG (1-7)/Mas receptor, the prorenin/prorenin receptor (PRR), and the ANG IV/AT4 receptor (IRAP) pathways. Accordingly, the roles of the RAS have expanded well beyond the classic endocrine paradigm as a powerful vasoconstrictor, a potent aldosterone stimulator, or a sodium-retaining hormonal system. The goals of this article are to review and discuss the current insights into and new perspectives on the expression, localization, and novel actions of the RAS with a focus in the kidney. Special emphasis will be placed on recently discovered new members of the RAS derived from studies using innovative mutant rats or mice that either overexpress (knockin) or are deficient (knockout) of a particular substrate, enzyme, ANG peptide, or receptor. This new knowledge will help improve our understanding how each of these pathways act directly or indirectly to regulate blood pressure, cardiovascular and kidney function in physiology, and can be targeted to treat hypertension, cardiovascular and renal diseases.

Product Identifiers

Publisher
Morgan & Claypool Publishers
ISBN-13
9781615046744
eBay Product ID (ePID)
214067229

Product Key Features

Author
Xiao C. Li, Jia L. Zhuo
Publication Name
The Renin-Angiotensin System and the Kidney: New Insights and Perspectives
Format
Paperback
Language
English
Subject
Psychiatry
Publication Year
2015
Type
Textbook
Number of Pages
61 Pages

Dimensions

Item Height
235mm
Item Width
191mm
Item Weight
333g

Additional Product Features

Title_Author
Xiao C. Li, Jia L. Zhuo
Series Title
Colloquium Series on Integrated Systems Physiology: from Molecule to Function
Country/Region of Manufacture
United States

Best Selling in Adult Learning & University

Current slide {CURRENT_SLIDE} of {TOTAL_SLIDES}- Best Selling in Adult Learning & University

Eduqas GCSE (9-1) Religious Studies Route B: Catholic Christianity and Judaism by Deirdre Cleary, Andrew Barron, Joy White, Patrick Harrison (Paperback, 2017)
No ratings or reviews yet.
AU $101.98 New
---- Used
Polyvagal Exercises for Safety and Connection: 50 Client-Centered Practices by Deb Dana (Paperback, 2020)
No ratings or reviews yet.
AU $53.04 New
AU $45.00 Used

Save on Adult Learning & University

Current slide {CURRENT_SLIDE} of {TOTAL_SLIDES}- Save on Adult Learning & University

Weed Forager's Handbook: A Guide to Edible and Medicinal Weeds in Australia by A
AU $19.95
Trending at AU $20.60
Netter Atlas of Human Anatomy: Classic Regional Approach
AU $113.94
Trending at AU $121.83
Michael Nehls The Indoctrinated Brain (Hardback) (US IMPORT)
AU $59.80
Trending at AU $63.46
Bill Perkins Die With Zero (Paperback)
AU $29.80
Trending at AU $32.49
Havard's Nursing Guide to Drugs
AU $75.00
Trending at AU $76.54
Nelson Senior Maths 11 Mathematics Essential Student Book with 1 Access Code for
AU $84.49
Trending at AU $85.68

Shop by category

The Renin-Angiotensin System and the Kidney: New Insights and Perspectives by Xiao C. Li, Jia L. Zhuo (Paperback, 2015)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

Best Selling in Adult Learning & University

Eduqas GCSE (9-1) Religious Studies Route B: Catholic Christianity and Judaism by Deirdre Cleary, Andrew Barron, Joy White, Patrick Harrison (Paperback, 2017)

Polyvagal Exercises for Safety and Connection: 50 Client-Centered Practices by Deb Dana (Paperback, 2020)

Save on Adult Learning & University

Weed Forager's Handbook: A Guide to Edible and Medicinal Weeds in Australia by A

Netter Atlas of Human Anatomy: Classic Regional Approach

Michael Nehls The Indoctrinated Brain (Hardback) (US IMPORT)

Bill Perkins Die With Zero (Paperback)

Havard's Nursing Guide to Drugs

Nelson Senior Maths 11 Mathematics Essential Student Book with 1 Access Code for

You may also like

New York Paperbacks

New Zealand Paperbacks

Insight Guides & Fiction Paperback Non-Fiction Books

Fiction & L. Frank Baum Paperback Books

Fiction Paperback Dorothy L. Sayers & Fiction Books

Paperback Calendars (Current)