After the identification of a potential protein drug, the next critical step is the production of sufficient authentic material for testing, characterization, and clinical trials, which, when successful, leads to the need for robust methodologies for large-scale production, purification, characterization, viral inactivation, and continued testing of the final protein product. Building on the valuable first edition, Therapeutic Proteins: Methods and Protocols, Second Edition aims to cover each of these key aspects of protein drug production through the contributions of authors from highly esteemed industrial and academic institutions around the world. Emphasizing the newest developments in the field, this second edition also includes additional emphasis on discovery, including new display and screening methods as well as the design and engineering of new types of therapeutic proteins. There is also discussion of computational and bioinformatics methods, and chapters on safety aspects of therapeutic protein development. Written in the highly successful Methods in Molecular Biology (TM) format, protocol chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding kwn pitfalls. Fully updated and practical, Therapeutic Proteins: Methods and Protocols, Second Edition provides an essential resource to all scientists working in the field of therapeutic proteins.
Product Identifiers
Publisher
Humana Press Inc.
ISBN-10
1617799203
ISBN-13
9781617799204
eBay Product ID (ePID)
114426695
Product Key Features
Format
Hardback
Language
English
Subject
Clinical Medicine: Professional
Dimensions
Weight
1154g
Height
254mm
Width
178mm
Additional Product Features
Place of Publication
Totowa, NJ
Edited by
Justin A. Caravella, Vladimir Voynov
Series Part/Volume Number
899
Series Title
Methods in Molecular Biology
Content Note
32 Tables, Black and White; Xi, 502 P. 107 Illus., 50 Illus. in Color.