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Protein Pharmacokinetics and Metabolism by Bobbe L. Ferraiolo, Carol A. Gloff, Marjorie A. Mohler (Paperback, 2013)

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Investigation of the pharmacokinetics and metabolism of human proteins has escalated over the last two decades because of the use of recombinant human proteins as therapeutic agents. In addition, the development and improvement of analytical techniques enabling the detection of minute quantities of proteins in biological matrices have aided this process. In assembling this volume, we sought to provide a state-of-the-art as sessment of the pharmacokinetics and metabolism of protein therapeutics through complete reviews of selected examples. A comprehensive review of all protein therapeutics was not attempted; the majority -of the therapeutic protein classes and crucial scientific issues have been addressed, however. Therefore, we are confident that this volume will provide a useful reference for scientists in this field. The volume has been divided into two general parts. The first part (Chapters 1-3) is composed of general reviews of topics of importance in pharmacokinetic/metabolism studies of proteins: goals and analytical meth odologies, effects of binding proteins, and effects of antibody induction, respectively. The second part (Chapters 4-8) consists of specific, detailed reviews by therapeutic protein class: growth factors and hormones, cyto kines, cardiovascular proteins, hematopoietic proteins, and antibodies, respectively. The editors are grateful to the contributors for the patience, personal sacrifice and perseverance required to complete this volume. BoDDE L. FERRAIOLO MARJORIE A. MOHLER CAROL A. GLOFF ix Contents Chapter 1 Goals and Analytical Methodologies for Protein Disposition Studies Bobbe L. Ferraiolo and Marjorie A. Mohler 1. Introduction ................................................. .

Product Identifiers

Publisher
Springer-Verlag New York Inc.
ISBN-13
9781489923318
eBay Product ID (ePID)
189481439

Product Key Features

Author
Bobbe L. Ferraiolo, Carol A. Gloff, Marjorie A. Mohler
Publication Name
Protein Pharmacokinetics and Metabolism
Format
Paperback
Language
English
Subject
Medicine, Chemistry, Pharmacy
Publication Year
2013
Type
Textbook
Number of Pages
276 Pages

Dimensions

Item Height
235mm
Item Width
155mm
Volume
1
Item Weight
450g

Additional Product Features

Series Title
Pharmaceutical Biotechnology
Country/Region of Manufacture
United States
Editor
Carol A. Gloff, Marjorie A. Mohler, Bobbe L. Ferraiolo

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Protein Pharmacokinetics and Metabolism by Bobbe L. Ferraiolo, Carol A. Gloff, Marjorie A. Mohler (Paperback, 2013)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

Best Selling in Adult Learning & University

Permaculture: A Designer's Manual by Bill Mollison (Hardcover, 1988)

Australian Native Bee Book: Keeping Stingless Bee Hives for Pets, Pollination and Sugarbag Honey by Tim Heard (Paperback, 2015)

The Weed Forager's Handbook: A Guide to Edible and Medicinal Weeds in Australia by Adam Grubb, Annie Raser-Rowland (2012, Paperback)

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Empire of the Summer Moon: Quanah Parker and the Rise and Fall of the Comanches, the Most Powerful Indian Tribe in American History by S.C. Gwynne (Paperback, 2011)

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