Edited by three pioneers in the field, each with longstanding experience in the biotech industry, and a skilled scientific writer, this is the first book to cover every step in the development and production of immunoglobulin Fc-fusion proteins as therapeutics for human disease: from choosing the right molecular design, to pre-clinical characterization of the purified product, through to batch optimization and quality control for large-scale cGMP production. The whole of the second part is devoted to case studies of Fc-fusion proteins that are now commercially successful products. In this section, the authors, several of whom were personally involved in clinical development of the products themselves, detail the product?s background and give insight into issues that were faced and how these issues were overcome during clinical development. This section also includes a chapter on promising new developments for the future. An invaluable resource for professionals already working on Fc-fusion proteins and an excellent and thorough introduction for physicians, researchers, and students entering the field.
Product Identifiers
Publisher
Wiley-Vch Verlag Gmbh
ISBN-13
9783527333172
eBay Product ID (ePID)
190229911
Product Key Features
Subject Area
Bioengineering
Author
Henry B. Lowman, Steven M. Chamow, Thomas Ryll, Deborah Farson
Publication Name
Therapeutic FC-Fusion Proteins
Format
Hardcover
Language
English
Subject
Chemistry
Publication Year
2014
Type
Textbook
Number of Pages
400 Pages
Dimensions
Item Height
250mm
Item Width
172mm
Item Weight
1012g
Additional Product Features
Editor
Steven M. Chamow, Deborah Farson, Thomas Ryll, Henry B. Lowman