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Death Receptors and Cognate Ligands in Cancer by Holger Kalthoff (Paperback, 2012)

About this product

About this product

Product Information

Death receptors play a central role in directing apoptosis in mammalian cells. This process of active cell death is important for a number of biological processes, e.g. for the regulation of the immune system. Death receptors are cell surface receptors that transmit apoptotic signals initiated by corresponding death ligands. Many complex signaling pathways are activated and apoptosis is the final result of a complex biochemical cascade of events. Besides their role in the induction of cell death, evidence now exists that death receptors are able to activate several non-apoptotic signaling pathways which, depending on cellular context, may lead to apoptosis resistance, secretion of pro-inflammatory proteins, proliferation and invasive growth of cancer cells. This book looks at the molecular basis of death receptor signaling and the role of death receptors in cancer development.

Product Identifiers

Publisher
Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg
ISBN-13
9783642260766
eBay Product ID (ePID)
128787389

Product Key Features

Author
Holger Kalthoff
Publication Name
Death Receptors and Cognate Ligands in Cancer
Format
Paperback
Language
English
Subject
Medicine, Chemistry, Biology
Publication Year
2012
Type
Textbook
Number of Pages
280 Pages

Dimensions

Item Height
235mm
Item Width
155mm
Volume
49
Item Weight
456g

Additional Product Features

Series Title
Results and Problems in Cell Differentiation
Editor
Holger Kalthoff
Country/Region of Manufacture
Germany

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