The glycogen content of rmal mammalian CNS is small when compared with that of some other mammalian tissues such as liver and muscle. Nevertheless, this glycogen content rmally comprises at least one quarter of its total reserve of energy, the rest being adesine triphosphate (ATP), phosphocreatine and glucose. Since this glycogen undergoes a turver 50-100 times that of brain lipids, and exceeds by several orders of magnitude that of liver glycogen, it most likely plays a dynamic role in the metabolism of brain, Gatfield et al. (1966), Prasannan and Subrahmanyam (1968b), Brunner et al. (1971), Edwards and Rogers (1972) and Watanabe and Passonneau (1973). Glycogen also has an unequal distribution in the rmal mammalian brain and spinal cord (Shimizu and Kumamoto, 1952; Shimizu and Okada, 1957; Friede, 1966; Shanthaveerappa et al. , 1966; Ibrahim etal. , 1970a), and it is possible that areas showing more glycogen are inherently vulnerable and that their extra glycogen is an added protective mechanism (Ibrahim, 1972). However, this is probably t the only explanation for the unequal distribution of glycogen since it is suggested for instance that neuronal glycogen may be rmally impli- cated in the process of synaptic transmission (Shanthaveerappa et al. , 1966; Drummond and Bellward, 1970) and that retinal glycogen plays a role in the rmal dark-light adaptation sequence (Shimizu and Maeda, 1953). Also, a wide variety of physiological, pathological and experimental conditions leads to a common response in the CNS, namely, accumulation of glycogen.
Product Identifiers
Publisher
Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg, Springer-Verlag Berlin and Heidelberg Gmbh & Co. K
ISBN-10
3540074546
ISBN-13
9783540074540
eBay Product ID (ePID)
190425910
Product Key Features
Author
M. Z. M. Ibrahim
Format
Paperback
Language
English
Subject
Medicine: General
Dimensions
Weight
190g
Height
244mm
Width
170mm
Additional Product Features
Place of Publication
Berlin
Spine
5mm
Issn
0301-5556
Series Part/Volume Number
52/1
Series Title
Advances in Anatomy, Embryology and Cell Biology
Content Note
49 Black & White Illustrations, Biography
Date of Publication
01/12/1975
Genre
Medicine: General
Country of Publication
Germany
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