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Quantitative Modeling in Toxicology by Kannan Krishnan, Melvin E. Andersen (Hardcover, 2010)

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Author: Kannan Krishnan. the quantitative models of pharmacokinetics of individual chemicals and mixtures. Title: Quantitative Modeling in Toxicology. InQuantitative Modeling in Toxicology leading experts outline the current state of knowledge on the modeling of dose, tissue interactions and tissue responses.

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Product Information

Governments around the world are passing laws requiring industry to assess the toxicity of the chemicals and products they produce, but to do so while reducing, refining, or even replacing testing on animals. To meet these requirements, experimental toxicologists and risk assessors are adopting quantitative approaches and computer simulations to study the biological fate and effects of chemicals and drugs. In Quantitative Modeling in Toxicology leading experts outline the current state of knowledge on the modeling of dose, tissue interactions and tissue responses. Each chapter describes the mathematical foundation, parameter estimation, challenges and perspectives for development, along with the presentation of a modeling template. Additionally, tools and approaches for conducting uncertainty, sensitivity and variability analyses in these models are described. Topics covered include: the quantitative models of pharmacokinetics of individual chemicals and mixtures models for toxicant-target tissue interaction. models for cellular, organ, and organism responses. approaches, tools and challenges for model application and evaluation A website containing computer codes accompanies the book to help the reader reconstruct the models described and discussed in the various chapters. Quantitative Modeling in Toxicology serves as an essential reference source and tool box for risk assessors and researchers and students in toxicology, public health, pharmacology, and human toxicology interested in developing quantitative models for a better understanding of dose-response relationships.

Product Identifiers

Publisher
John Wiley & Sons Inc
ISBN-13
9780470998090
eBay Product ID (ePID)
96884347

Product Key Features

Author
Kannan Krishnan, Melvin E. Andersen
Publication Name
Quantitative Modeling in Toxicology
Format
Hardcover
Language
English
Subject
Medicine
Publication Year
2010
Type
Textbook
Number of Pages
504 Pages

Dimensions

Item Height
250mm
Item Width
177mm
Item Weight
978g

Additional Product Features

Country/Region of Manufacture
United States
Editor
Melvin E. Andersen, Kannan Krishnan

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Picture 1 of 1

Quantitative Modeling in Toxicology by Kannan Krishnan, Melvin E. Andersen (Hardcover, 2010)

About this product

Product Information

Product Identifiers

Product Key Features

Dimensions

Additional Product Features

Best Selling in Adult Learning & University

Australian Guidebook for Structural Engineers by Lonnie Pack (Paperback, 2019)

Eduqas GCSE (9-1) Religious Studies Route B: Catholic Christianity and Judaism by Deirdre Cleary, Andrew Barron, Joy White, Patrick Harrison (Paperback, 2017)

The Ethnic Cleansing of Palestine by Ilan Pappe (Paperback, 2007)

Save on Adult Learning & University

The Australian Native Bee Hive Book: Keeping Stingless Sugarbag OATH Tim Heard

Weed Forager's Handbook: A Guide to Edible and Medicinal Weeds in Australia by A

Netter Atlas of Human Anatomy: Classic Regional Approach

George Hrabovsky Leonard Susskind Classical Mechanics (Paperback)

Havard's Nursing Guide to Drugs

Phillip J. Anderson The Secret Life of Real Estate and Banking (Hardback)

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