Picture 1 of 1
Picture 1 of 1
La mucoviscidose: correction par sur-expression de nhe-rf1.978613
GBP 105.66
ApproximatelyAU $202.50
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5 available
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Located in: South East, United Kingdom
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eBay item number:126297453974
Item specifics
- Condition
- PublishedOn
- 2011-05-19
- Title
- La mucoviscidose: correction par sur-expression de nhe-rf1
- ISBN
- 9786131564055
- Publication Year
- 2018
- Type
- Textbook
- Format
- Paperback
- Language
- French
- Book Title
- La Mucoviscidose: Correction Par Sur-Expression De Nhe-Rf1
- Item Height
- 229mm
- Publisher
- Omniscriptum
- Topic
- Literature, Biology
- Item Width
- 152mm
- Item Weight
- 313g
- Number of Pages
- 208 Pages
About this product
Product Information
Apr s une description de la mucoviscidose, cet ouvrage pr sente les r sultats de deux tudes scientifiques. La premi re s'int resse l'impact d'une prot ine partenaire de CFTR, NHE-RF1, sur la prot ine mut e la plus fr quente dans la mucoviscidose: DeltaF508. Cette tude d montre que la sur-expression de NHE-RF1 corrige le d faut d'adressage de DeltaF508 et restaure une activit partielle. La seconde tude compare l'expression des r cepteurs beta-adr nergiques (b-AR) et de NHE-RF1 dans les poumons de patients sains et mucoviscidosiques. En effet, les b1 et b2-AR sont pr sents dans les poumons o ils r gulent diverses fonctions biologiques. Mais dans la mucoviscidose, la r ponse beta-adr nergique globale est alt r e. Ces travaux d montrent: 1) l'expression de b3-AR dans les poumons humains et 2) une modification d'expression des b-AR et de NHE-RF1 dans la mucoviscidose (sur-expression des b1 et b3-AR, sous-expression des b2-AR et NHE-RF1). L'implication physiopathologique de ce remodelage dans la mucoviscidose reste d finir. Enfin, la sous-expression de NHE-RF1 devra tre prise en compte pour les possibilit s de restauration pharmacologique des mutations chez les patients.
Product Identifiers
Publisher
Omniscriptum
ISBN-13
9786131564055
eBay Product ID (ePID)
205542837
Product Key Features
Book Title
La Mucoviscidose: Correction Par Sur-Expression De Nhe-Rf1
Format
Paperback
Language
French
Topic
Literature, Biology
Publication Year
2018
Type
Textbook
Number of Pages
208 Pages
Dimensions
Item Height
229mm
Item Width
152mm
Item Weight
313g
Additional Product Features
Series Title
Omn.Univ.Europ.
Item description from the seller
Business seller information
Value Added Tax number:
- GB 724498118
Seller assumes all responsibility for this listing.
eBay item number:126297453974
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Item location:
South East, United Kingdom
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