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Kannan Krishnan Quantitative Modeling in Toxicology (Hardback) (US IMPORT)

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Item specifics

Condition
Brand new: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ...
Book Title
Quantitative Modeling in Toxicology
Title
Quantitative Modeling in Toxicology
Contributor
Kannan Krishnan (Edited by)
EAN
9780470998090
ISBN
9780470998090
Genre
Medicine
Release Date
26/03/2010
Release Year
2010
Country/Region of Manufacture
US
Item Length
177mm
Publication Year
2010
Type
Textbook
Format
Hardcover
Language
English
Publication Name
Quantitative Modeling in Toxicology
Item Height
250mm
Author
Kannan Krishnan, Melvin E. Andersen
Publisher
John Wiley & Sons Inc
Item Width
177mm
Subject
Medicine
Item Weight
978g
Number of Pages
504 Pages

About this product

Product Information

Governments around the world are passing laws requiring industry to assess the toxicity of the chemicals and products they produce, but to do so while reducing, refining, or even replacing testing on animals. To meet these requirements, experimental toxicologists and risk assessors are adopting quantitative approaches and computer simulations to study the biological fate and effects of chemicals and drugs. In Quantitative Modeling in Toxicology leading experts outline the current state of knowledge on the modeling of dose, tissue interactions and tissue responses. Each chapter describes the mathematical foundation, parameter estimation, challenges and perspectives for development, along with the presentation of a modeling template. Additionally, tools and approaches for conducting uncertainty, sensitivity and variability analyses in these models are described. Topics covered include: the quantitative models of pharmacokinetics of individual chemicals and mixtures models for toxicant-target tissue interaction. models for cellular, organ, and organism responses. approaches, tools and challenges for model application and evaluation A website containing computer codes accompanies the book to help the reader reconstruct the models described and discussed in the various chapters. Quantitative Modeling in Toxicology serves as an essential reference source and tool box for risk assessors and researchers and students in toxicology, public health, pharmacology, and human toxicology interested in developing quantitative models for a better understanding of dose-response relationships.

Product Identifiers

Publisher
John Wiley & Sons Inc
ISBN-13
9780470998090
eBay Product ID (ePID)
96884347

Product Key Features

Author
Kannan Krishnan, Melvin E. Andersen
Publication Name
Quantitative Modeling in Toxicology
Format
Hardcover
Language
English
Subject
Medicine
Publication Year
2010
Type
Textbook
Number of Pages
504 Pages

Dimensions

Item Height
250mm
Item Width
177mm
Item Weight
978g

Additional Product Features

Country/Region of Manufacture
United States
Editor
Melvin E. Andersen, Kannan Krishnan

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