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DNA Replication and Human Disease by Melvin L. DePamphilis (English) Hardcover B
AU $281.28
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eBay item number:145387496589
Item specifics
- Condition
- ISBN-13
- 9780879697662
- Book Title
- DNA Replication and Human Disease
- ISBN
- 9780879697662
- Publication Year
- 2006
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Publication Name
- D N A Replication and Human Disease
- Item Height
- 236mm
- Publisher
- Cold Spring Harbor Laboratory Press,U.S.
- Item Width
- 161mm
- Subject
- Biology
- Item Weight
- 1400g
- Number of Pages
- 814 Pages
About this product
Product Information
At least 5 trillion cell divisions are required for a fertilized egg to develop into an adult human, resulting in the production of more than 20 trillion meters of DNA! And yet, with only two exceptions, the genome is replicated once and only once each time a cell divides. How is this feat accomplished? What happens when errors occur? This book addresses these questions by presenting a thorough analysis of the molecular events that govern DNA replication in eukaryotic cells. The association between genome replication and cell proliferation, disease pathogenesis, and the development of targeted therapeutics is also addressed. At least 160 proteins are involved in replicating the human genome, and at least 40 diseases are caused by aberrant DNA replication, 35 by mutations in genes required for DNA replication or repair, 7 by mutations generated during mitochondrial DNA replication, and more than 40 by DNA viruses. Consequently, a growing number of therapeutic drugs are targeted to DNA replication proteins. This authoritative volume provides a rich source of information for researchers, physicians, and teachers, and will stimulate thinking about the relevance of DNA replication to human disease.
Product Identifiers
Publisher
Cold Spring Harbor Laboratory Press,U.S.
ISBN-13
9780879697662
eBay Product ID (ePID)
94707147
Product Key Features
Publication Name
D N A Replication and Human Disease
Format
Hardcover
Language
English
Subject
Biology
Publication Year
2006
Type
Textbook
Number of Pages
814 Pages
Dimensions
Item Height
236mm
Item Width
161mm
Volume
No. 47
Item Weight
1400g
Additional Product Features
Issn
0270-1847
Series Title
Cold Spring Harbor Monograph Series
Country/Region of Manufacture
United States
Editor
Melvin L. Depamphilis
Item description from the seller
Business seller information
Value Added Tax number:
- AU 82107909133
- GB 293967539
Seller assumes all responsibility for this listing.
eBay item number:145387496589
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| Postage and handling | To | Service | Delivery*See delivery notes |
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