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Bioisosteres in Medicinal Chemistry by Nathan Brown (English) Hardcover Book
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- Buy It NowBioisosteres in Medicinal Chemistry by Nathan Brown (English) Hardcover Book
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eBay item number:155899565137
Item specifics
- Condition
- ISBN-13
- 9783527330157
- Book Title
- Bioisosteres in Medicinal Chemistry
- ISBN
- 9783527330157
- Subject Area
- Chemical Engineering
- Publication Name
- Bioisosteres in Medicinal Chemistry
- Publisher
- Wiley-Vch Verlag Gmbh
- Subject
- Medicine
- Publication Year
- 2012
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Item Height
- 258mm
- Item Width
- 170mm
- Item Weight
- 628g
- Number of Pages
- 256 Pages
About this product
Product Information
Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologies for bioisostere identification and replacement: physicochemical properties, topology, shape, and overlays of protein-ligand crystal structures. In the final part, several real-world examples of bioisosterism in drug discovery projects are discussed. With its detailed descriptions of databases, methods and real-life case studies, this is tailor-made for busy industrial researchers with little time for reading, while remaining easily accessible to novice drug developers due to its systematic structure and introductory section.
Product Identifiers
Publisher
Wiley-Vch Verlag Gmbh
ISBN-13
9783527330157
eBay Product ID (ePID)
114420789
Product Key Features
Subject Area
Chemical Engineering
Publication Name
Bioisosteres in Medicinal Chemistry
Format
Hardcover
Language
English
Subject
Medicine
Publication Year
2012
Type
Textbook
Number of Pages
256 Pages
Dimensions
Item Height
258mm
Item Width
170mm
Item Weight
628g
Additional Product Features
Series Title
Methods & Principles in Medicinal Chemistry
Editor
Nathan Brown
Country/Region of Manufacture
Germany
Item description from the seller
Business seller information
Value Added Tax number:
- AU 82107909133
- GB 293967539
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eBay item number:155899565137
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