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Fibrosis Research: Methods and Protocols

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Condition:
Very good
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Last updated on 16 Jun, 2024 13:39:52 AESTView all revisionsView all revisions

Item specifics

Condition
Very good
A book that does not look new and has been read but is in excellent condition. No obvious damage to the cover, with the dust jacket (if applicable) included for hard covers. No missing or damaged pages, no creases or tears, and no underlining/highlighting of text or writing in the margins. May be very minimal identifying marks on the inside cover. Very minimal wear and tear. See the seller’s listing for full details and description of any imperfections. See all condition definitionsopens in a new window or tab
Seller notes
β€œMay have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend ...
Binding
Hardcover
Weight
1 lbs
Product Group
Book
IsTextBook
No
ISBN
9781588294791
Subject Area
Medical
Publication Name
Fibrosis Research : Methods and Protocols
Item Length
9.3 in
Publisher
Humana Press
Subject
Pulmonary & Thoracic Medicine, Diseases
Series
Methods in Molecular Medicine Ser.
Publication Year
2005
Type
Textbook
Format
Hardcover
Language
English
Author
David A. Brenner
Item Width
6.1 in
Item Weight
30.2 Oz
Number of Pages
Xvi, 392 Pages

About this product

Product Information

Leading investigators review the highlights of current fibrosis research and the experimental methodologies used uncover the mechanisms that drive it. In their discussion of research methodologies utilizing cultured cells to model various aspects of the fibrotic response in vitro, the authors describe the isolation, characterization, and propagation of mesenchymal cells, and highlight the similarities and differences between methods that are appropriate for different types of fibroblasts. Approaches for studying collagen gene regulation and TGF-b production are also discussed, along with experimental methodologies utilizing animal models to study the pathogenesis of fibrosis. The protocols follow the successful Methods in Molecular Medicine(TM) series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

Product Identifiers

Publisher
Humana Press
ISBN-10
158829479x
ISBN-13
9781588294791
eBay Product ID (ePID)
8038619046

Product Key Features

Author
David A. Brenner
Publication Name
Fibrosis Research : Methods and Protocols
Format
Hardcover
Language
English
Subject
Pulmonary & Thoracic Medicine, Diseases
Series
Methods in Molecular Medicine Ser.
Publication Year
2005
Type
Textbook
Subject Area
Medical
Number of Pages
Xvi, 392 Pages

Dimensions

Item Length
9.3 in
Item Width
6.1 in
Item Weight
30.2 Oz

Additional Product Features

LCCN
2005-006567
Intended Audience
Scholarly & Professional
Series Volume Number
117
Number of Volumes
1 Vol.
Lc Classification Number
Rc705-779
Reviews
"...a must for the shelf of every researcher and physician interested in fibrotic diseases." -Rheumatology
Table of Content
The Clinical Scope of Fibrosis.- Pulmonary Fibrosis.- Renal Fibrosis.- Transforming Growth Factor-?.- Regulation of Extracellular Matrix Metabolism: Cultured Cells.- Isolation and Culture of Skin Fibroblasts.- Isolation and Culture of Hepatic Stellate Cells.- Isolation and Phenotypic Characterization of Lung Fibroblasts.- Methods for Measuring Type I Collagen Synthesis In Vitro.- Methods for Assessing the Molecular Mechanisms Controlling Gene Regulation.- Methods for Measuring TGF-? Using Antibodies, Cells, and Mice.- Studying Fibrosis Using Animal Models.- Morphological Methods for Assessment of Fibrosis.- Methods for Measuring Hydroxyproline and Estimating In Vivo Rates of Collagen Synthesis and Degradation.- Approaches to Evaluation of Fibrogenic Pathways in Surgical Lung Biopsy Specimens.- Animal Models for Adult Dermal Wound Healing.- Modeling Liver Fibrosis in Rodents.- Animal Models of Pulmonary Fibrosis.- Animal Models of Renal Fibrosis.- Animal Models of Cardiac Fibrosis.- Genetic Approaches to Studying Fibrosis.- Finding Fibrosis Genes.- Genetic Studies to Identify Hepatic Fibrosis Genes and SNPs in Human Populations.- Analysis of Microarray Experiments for Pulmonary Fibrosis.- DNA Microarrays and Data Mining To Study Hepatic Fibrosis.- Analysis of Proteins Dominantly Expressed in Hepatic Stellate Cells of Activated Phenotype.
Copyright Date
2005
Dewey Decimal
616.7/42
Dewey Edition
22
Illustrated
Yes

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