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Toxicology of Glutathione Transferases - 9780849329838
GBP 149.42
ApproximatelyAU $291.65
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eBay item number:285342354106
Item specifics
- Condition
- Book Title
- Toxicology of Glutathione Transferases
- ISBN
- 9780849329838
- Publication Year
- 2006
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Publication Name
- Toxicology of Glutathione Transferases
- Item Height
- 234 mm
- Publisher
- Taylor & Francis INC International Concepts
- Subject
- Chemistry, Biology
- Item Weight
- 726 g
- Item Width
- 156 mm
- Number of Pages
- 375 Pages
About this product
Product Information
Since the discovery of Glutathione S-Transferase (GST) or Glutathione transferase, studies have probed important questions about its pharmacological and physiological significance. Toxicology of Glutathione Transferases is the only text that details the methods used in GST research. With chapters written by experts who have been involved in all areas of GST research and have actively contributed to the progress of this field, the book describes the role of GSTs in toxicology, focusing on their pharmacologic and physiologic roles and their relevance to biological toxicology. The book provides current information on gene families, structure and regulation of gene expression, reaction mechanisms and substrates, three-dimensional structures of GSTs, design of proteins with GST activity, and various approaches to developing inhibitors that overcome drug resistance. It also covers the physiological significance and the mechanisms of activation of microsomal GSTs. These topics, along with the role of GSTs in detoxification of chemical carcinogens and possible implications of GST polymorphism in human health and disease, make the volume useful to researchers in the field of pharmacology and toxicology. Chapters cover the possible and exciting role of GSTs in defense mechanisms against chronic oxidative stress-linked disorders such as atherosclerosis and the newly emerging area of GST-mediated modulation of stress-signaling through its catalytic as well as binding activities. They explore an intriguing hypothesis that strongly suggests an important role of the factors that modulate the GSH-electrophile conjugate (GS-E) homeostasis in the regulation of cellular processes. Chapters on known and potential endogenous electrophilic substrates and a major role of GSTs in suppressing stress-induced lipid peroxidation reinforce this newly emerging role of GSTs. These are just a few of the features that make the book helpful to clinicians involved in basic as well as tr
Product Identifiers
Publisher
Taylor & Francis INC International Concepts
ISBN-13
9780849329838
eBay Product ID (ePID)
88915107
Product Key Features
Number of Pages
375 Pages
Language
English
Publication Name
Toxicology of Glutathione Transferases
Publication Year
2006
Subject
Chemistry, Biology
Type
Textbook
Format
Hardcover
Dimensions
Item Height
234 mm
Item Weight
726 g
Item Width
156 mm
Additional Product Features
Editor
Yogesh C. Awasthi
Country/Region of Manufacture
United States
Item description from the seller
Business seller information
Value Added Tax number:
- GB 976952259
Seller Feedback (530,593)
- s***l (80)- Feedback left by buyer.Past 6 monthsVerified purchaseAs described, favourable price, well packed, delivered on time and I was kept fully informed about despatch and delivery. An excellent book, too. I have used this seller previously with very professional service and will no doubt do so again.
- t***n (433)- Feedback left by buyer.Past monthVerified purchaseQuick delivery well packaged,communication with seller good... exactly as described by seller and decent price too...good seller
- 6***j (73)- Feedback left by buyer.Past 6 monthsVerified purchaseThe book was as described. Excellent value and good service. Very well packaged, delivery was accurate enough and good communication. Will be happy to buy from again. Many thanksWoodcarving Magic - 9781565235236 (#314126641264)