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Reviews of Physiology, Biochemistry and Pharmacology 147 - 9783642056833

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Item specifics

Condition
Brand new: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ...
Book Title
Reviews of Physiology, Biochemistry and Pharmacology 147
ISBN
9783642056833
Publication Year
2010
Type
Textbook
Format
Paperback
Language
English
Publication Name
Reviews of Physiology, Biochemistry and Pharmacology 147
Item Height
235mm
Author
Not Available
Publisher
Springer-Verlag Berlin AND Heidelberg Gmbh & Co. KG, R. Hogg, J. Eckert, D. Bertrand, B. Ludwig, C. Andersen, M. Raggenbass, O. Richter, R. Erdmann
Item Width
155mm
Subject
Medicine
Item Weight
272g
Number of Pages
165 Pages

About this product

Product Information

Ligand-gated ion channels mediate fast synaptic transmission in the central nervous s- tem (CNS) and at ganglionic and neuromuscular synapses. The nicotinic acetylcholine - ceptor (nAChR) is a member of the ligand-gated ion channel superfamily, which includes the 5-HT , glycine and GABA type A and C receptors. These receptors are known as Cys- 3 loop receptors, as all of them have a conserved sequence containing a pair of cysteines separated by 13 residues and linked by a disulfide bridge. nAChRs can be divided into two groups: muscle receptors, which are found at the skeletal neuromuscular junction where they mediate neuromuscular transmission, and neuronal receptors, which are found throughout the peripheral and central nervous system. Many of the early studies carried out on the subunit composition and structure of the nAChRs were performed on receptors isolated from the electric organ of Torpedo californica, as this tissue is very rich in nAChRs, and they were found to have a high degree of homology with the embryonic v- tebrate muscle type receptor. Muscle nAChRs are made up of five subunits arranged around a central pore (Fig. 1A, B). In Torpedo electric organ and vertebrate fetal muscle, the subunit composition is (a1) b1gd, and in adult muscle the g subunit is replaced by the e to give an (a1)b1ed 2 2 composition (Mishina et al. 1986).

Product Identifiers

Publisher
Springer-Verlag Berlin AND Heidelberg Gmbh & Co. KG, R. Hogg, J. Eckert, D. Bertrand, B. Ludwig, C. Andersen, M. Raggenbass, O. Richter, R. Erdmann
ISBN-13
9783642056833
eBay Product ID (ePID)
178224895

Product Key Features

Author
Not Available
Publication Name
Reviews of Physiology, Biochemistry and Pharmacology 147
Format
Paperback
Language
English
Subject
Medicine
Publication Year
2010
Type
Textbook
Number of Pages
165 Pages

Dimensions

Item Height
235mm
Item Width
155mm
Volume
147
Item Weight
272g

Additional Product Features

Series Title
Reviews of Physiology, Biochemistry and Pharmacology
Country/Region of Manufacture
Germany

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  • GB 976952259
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