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Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell B... - 9781461458937
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- Buy It NowProminin-1 (CD133): New Insights on Stem & Cancer Stem Cell B... - 9781461458937
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Located in: Aldershot, United Kingdom
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Item specifics
- Condition
- Book Title
- Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Bi...
- ISBN
- 9781461458937
- Publication Year
- 2012
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Publication Name
- Prominin-1 (Cd133) : New Insights on Stem & Cancer Stem Cell Biology
- Item Height
- 235mm
- Publisher
- Springer-Verlag New York Inc.
- Item Width
- 155mm
- Subject
- Medicine, Chemistry, Biology
- Item Weight
- 5266g
- Number of Pages
- 252 Pages
About this product
Product Information
Prominin-1 or otherwise known as CD133 is a glycoprotein that is present in humans and mice. Since the first description of prominin in 1997, in mouse neuroepithelial cells and in human hematopoietic stem cells as AC133 antigen, this molecule has aroused a large interest especially, as a stem cell marker, that gave rise to an ever growing body of publications and more recently its expression in cancer stem cells. Controversies as to its role as a cancer stem and its detection in different models, as well as its use as a prognostic marker have emerged. Yet, beyond its use as a stem cell and cancer stem cell marker, prominin-1/CD133 displays unique biological features and appears of importance in other processes like for example in retinal biogenesis. Indeed, this five-transmembrane plasma membrane glycoprotein, which marks membrane protrusions is associated with several essential processes like cell polarity, asymmetric cell division and membrane remodeling. We propose to review current knowledge about this intriguing molecule and present pertinent information to determine the biological role of prominins and assess their importance in medicine and cancer research. The primary audience for this book is geared towards scientists and researchers with interest in cancer stem cells, stem cells, cell biology, neurobiology, and regenerative medicine.
Product Identifiers
Publisher
Springer-Verlag New York Inc.
ISBN-13
9781461458937
eBay Product ID (ePID)
129267917
Product Key Features
Publication Name
Prominin-1 (Cd133) : New Insights on Stem & Cancer Stem Cell Biology
Format
Hardcover
Language
English
Subject
Medicine, Chemistry, Biology
Publication Year
2012
Type
Textbook
Number of Pages
252 Pages
Dimensions
Item Height
235mm
Item Width
155mm
Volume
777
Item Weight
5266g
Additional Product Features
Series Title
Advances in Experimental Medicine and Biology
Country/Region of Manufacture
United States
Editor
Denis Corbeil
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eBay item number:285361934264
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