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Effect of Plant Extracts on RNA Expression Profiles.9783844301724 New<|

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Item specifics

Condition
Brand new: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ...
PublishedOn
2011-02-02
Title
Effect of Plant Extracts on RNA Expression Profiles
ISBN
9783844301724
Publication Year
2011
Type
Textbook
Format
Paperback
Language
English
Publication Name
Effect of Plant Extracts on Rna Expression Profiles
Item Height
229mm
Author
Ruzaidi Azli Mohd Mokhtar, Valentino Milton Junior Gumbilai, Wilson Yong Thau Lym
Publisher
LAP
Item Width
152mm
Subject
Chemistry
Item Weight
141g
Number of Pages
88 Pages

About this product

Product Information

Diabetes is a major public health problem. The new therapies developments that are able to improve glycemia management, cure diabetes and even protect from it are of great interest. This study investigated the effect of selected plant extracts on the Insulin 2 gene expression profile against STZ- induced pancreatic cell damages. M.charantia extract showed the highest value of total phenolic content, antioxidant activity and total flavanoid content compared to M. citrifolia and P. speciosa extracts. Expression of both GAPDH as the reference gene and Ins2 gene as the target gene was measured by SYBR Green I fluorescence; melting curves and agarose gel electrophoresis were used to verify the specificity of gene (Ins2) for diabetic rats treated with M. charantia extracts expressing fold differences of 32 fold expression compare to the diabetic control rats only. This study report the preliminary study of the effect of plant extracts on the pancreatic cell insulin gene expression profile. The results represent an important step toward improved understanding of the regulation of insulin secretion on insulin 2 (Ins2) genes.

Product Identifiers

Publisher
LAP
ISBN-13
9783844301724
eBay Product ID (ePID)
99914120

Product Key Features

Author
Ruzaidi Azli Mohd Mokhtar, Valentino Milton Junior Gumbilai, Wilson Yong Thau Lym
Publication Name
Effect of Plant Extracts on Rna Expression Profiles
Format
Paperback
Language
English
Subject
Chemistry
Publication Year
2011
Type
Textbook
Number of Pages
88 Pages

Dimensions

Item Height
229mm
Item Width
152mm
Item Weight
141g

Additional Product Features

Title_Author
Valentino Milton Junior Gumbilai, Ruzaidi Azli Mohd Mokhtar, Wilson Yong Thau Lym
Country/Region of Manufacture
Germany

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Value Added Tax number:
  • GB 724498118
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