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Pharmaceutical Biotechnology Ser.: Protein Pharmacokineti
US $95.00
ApproximatelyAU $145.62
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A book that looks new but has been read. Cover has no visible wear, and the dust jacket (if applicable) is included for hard covers. No missing or damaged pages, no creases or tears, and no underlining/highlighting of text or writing in the margins. May be very minimal identifying marks on the inside cover. Very minimal wear and tear. See the seller’s listing for full details and description of any imperfections.
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eBay item number:326458410414
Item specifics
- Condition
- ISBN
- 9780306441516
About this product
Product Identifiers
Publisher
Springer
ISBN-10
0306441519
ISBN-13
9780306441516
eBay Product ID (ePID)
87115
Product Key Features
Number of Pages
Xvi, 276 Pages
Language
English
Publication Name
Protein Pharmacokinetics and Metabolism
Publication Year
1992
Subject
Life Sciences / Biochemistry, Pharmacy, Pharmacology
Type
Textbook
Subject Area
Science, Medical
Series
Pharmaceutical Biotechnology Ser.
Format
Hardcover
Dimensions
Item Weight
46.2 Oz
Item Length
9.2 in
Item Width
6.1 in
Additional Product Features
Intended Audience
Scholarly & Professional
LCCN
92-049392
Dewey Edition
20
Series Volume Number
1
Number of Volumes
1 vol.
Illustrated
Yes
Dewey Decimal
615.7
Table Of Content
1 Goals and Analytical Methodologies for Protein Disposition Studies.- 2 Binding Proteins of Protein Therapeutics.- 3 Potential Effects of Antibody Induction by Protein Drugs.- 4 Pharmacokinetics and Metabolism of Protein Hormones.- 5 Pharmacokinetics and Metabolism of Therapeutic Cytokines.- 6 Pharmacokinetics and Metabolism of Cardiovascular Therapeutic Proteins.- 7 Pharmacokinetics and Metabolism of Hematopoietic Proteins.- 8 Pharmacokinetics and Metabolism of Therapeutic and Diagnostic Antibodies.
Synopsis
Investigation of the pharmacokinetics and metabolism of human proteins has escalated over the last two decades because of the use of recombinant human proteins as therapeutic agents. In addition, the development and improvement of analytical techniques enabling the detection of minute quantities of proteins in biological matrices have aided this process. In assembling this volume, we sought to provide a state-of-the-art as- sessment of the pharmacokinetics and metabolism of protein therapeutics through complete reviews of selected examples. A comprehensive review of all protein therapeutics was not attempted; the majority -of the therapeutic protein classes and crucial scientific issues have been addressed, however. Therefore, we are confident that this volume will provide a useful reference for scientists in this field. The volume has been divided into two general parts. The first part (Chapters 1-3) is composed of general reviews of topics of importance in pharmacokinetic/metabolism studies of proteins: goals and analytical meth- odologies, effects of binding proteins, and effects of antibody induction, respectively. The second part (Chapters 4-8) consists of specific, detailed reviews by therapeutic protein class: growth factors and hormones, cyto- kines, cardiovascular proteins, hematopoietic proteins, and antibodies, respectively. The editors are grateful to the contributors for the patience, personal sacrifice and perseverance required to complete this volume. BoDDE L. FERRAIOLO MARJORIE A. MOHLER CAROL A. GLOFF ix Contents Chapter 1 Goals and Analytical Methodologies for Protein Disposition Studies Bobbe L. Ferraiolo and Marjorie A. Mohler 1. Introduction ................................................. ., Investigation of the pharmacokinetics and metabolism of human proteins has escalated over the last two decades because of the use of recombinant human proteins as therapeutic agents. In addition, the development and improvement of analytical techniques enabling the detection of minute quantities of proteins in biological matrices have aided this process. In assembling this volume, we sought to provide a state-of-the-art as sessment of the pharmacokinetics and metabolism of protein therapeutics through complete reviews of selected examples. A comprehensive review of all protein therapeutics was not attempted; the majority -of the therapeutic protein classes and crucial scientific issues have been addressed, however. Therefore, we are confident that this volume will provide a useful reference for scientists in this field. The volume has been divided into two general parts. The first part (Chapters 1-3) is composed of general reviews of topics of importance in pharmacokinetic/metabolism studies of proteins: goals and analytical meth odologies, effects of binding proteins, and effects of antibody induction, respectively. The second part (Chapters 4-8) consists of specific, detailed reviews by therapeutic protein class: growth factors and hormones, cyto kines, cardiovascular proteins, hematopoietic proteins, and antibodies, respectively. The editors are grateful to the contributors for the patience, personal sacrifice and perseverance required to complete this volume. BoDDE L. FERRAIOLO MARJORIE A. MOHLER CAROL A. GLOFF ix Contents Chapter 1 Goals and Analytical Methodologies for Protein Disposition Studies Bobbe L. Ferraiolo and Marjorie A. Mohler 1. Introduction ................................................. .
LC Classification Number
RM300-666
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Seller feedback (1,078)
- r***o (3449)- Feedback left by buyer.Past monthVerified purchaseItem as described. Extreme super--fast shipping, very safe delivery. Thanks again!!!!!
- y***y (17)- Feedback left by buyer.Past monthVerified purchaseQuick ship. Description was correct.
- o***n (434)- Feedback left by buyer.Past monthVerified purchaseItem arrived as described fast shipping.