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Condition:
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Item specifics

Condition
Like new
A book that looks new but has been read. Cover has no visible wear, and the dust jacket (if applicable) is included for hard covers. No missing or damaged pages, no creases or tears, and no underlining/highlighting of text or writing in the margins. May be very minimal identifying marks on the inside cover. Very minimal wear and tear. See the seller’s listing for full details and description of any imperfections. See all condition definitionsopens in a new window or tab
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“good condition”
ISBN
9780521885379

About this product

Product Identifiers

Publisher
Cambridge University Press
ISBN-10
052188537X
ISBN-13
9780521885379
eBay Product ID (ePID)
28038804603

Product Key Features

Number of Pages
282 Pages
Language
English
Publication Name
Principles of Pharmacogenetics and Pharmacogenomics
Subject
Life Sciences / Genetics & Genomics, Pharmacology
Publication Year
2012
Type
Textbook
Author
David Flockhart
Subject Area
Science, Medical
Format
Hardcover

Dimensions

Item Height
0.7 in
Item Weight
29.7 Oz
Item Length
10.3 in
Item Width
7.2 in

Additional Product Features

Intended Audience
Scholarly & Professional
LCCN
2011-018883
Dewey Edition
23
Illustrated
Yes
Dewey Decimal
615/.7
Table Of Content
Introduction to population diversity and genetic testing: basic concepts Russ Altman, David Flockhart and David Goldstein; Part I. Critical Concepts: 1. Introduction to population diversity and genetic testing James K. Burmester, Ingrid Glurich, Kimberly Pillsbury and Michael D. Caldwell; 2. Genotyping technologies Sharon Marsh and Cristi R. King; 3. Pharmacokinetics: absorption, distribution, metabolism, excretion Terry Blaschke; 4. Overview: adverse drug reactions Matthew Nelson; 5. PharmGKB, a centralized resource for pharmacogenomic knowledge and discovery Li Gong and Teri E. Klein; 6. DrugBank David S. Wishart; 7. Ethical considerations for pharmacogenomics: privacy and confidentiality Sandra Lee; 8. Informed consent in pharmacogenomic research and treatment Mark Rothstein; 9. Legal trends driving the clinical translation of pharmacogenomics Barbara Evans; Part II. Therapeutic Areas: 10. Pharmacogenetics of oncologic drugs Uchenna Njaju and Eileen Dolan; 11. Pharmacogenetics of cardiovascular drugs Michael Stein and Danny Kurnik; 12. Pharmacogenomics of statin-induced muscle toxicity Ronald M. Krauss, Russell A. Wilke, Melissa Antonik and Elenita Kanin; 13. Pharmacogenomics of the drug-induced long QT syndrome Dan M. Roden, Prince J. Kannankeril, Stefan Kaab and Dawood Darbar; 14. Pharmacogenetics of diabetes drugs O. H. Klungel and Mark C. H. DeGroot; 15. Pharmacogenetics of respiratory drugs Kelan Tantisira and Scott Weiss; 16. Pharmacogenomics for acid-related gastrointestinal drugs Takahisa Furuta; 17. Pharmacogenetics of rheumatoid arthritis drugs Robert M. Plenge, Yvonne C. Lee, Souomya Raychaudhuri and Daniel H. Solomon; 18. Pharmacogenomics of obstetric drugs David Haas and Jamie Renbarger; 19. Pharmacogenomics of psychiatric drugs David Mrazek; 20. Pharmacogenomics of pain and anesthesia drugs Evan Kharasch and Konrad Meissner; 21. Pharmacogenetics of HIV and antiretroviral drugs Amalio Telenti; 22. Pharmacogenomics in pediatrics Jennifer A. Lowry and J. Steven Leeder; 23. Pharmacogenomics in fetal and neonatal medicine Yair Blumenfeld.
Synopsis
The study of pharmacogenetics and pharmacogenomics focuses on how our genes and complex gene systems influence our response to drugs. Recent progress in the science of clinical therapeutics has led to the discovery of new biomarkers that make it technically easier to identify groups of patients which are more or less likely to respond to individual therapies. The aim is to improve personalised medicine - not simply to prescribe the right medicine, but to deliver the right drug at the right dose at the right time. This textbook brings together contributions from leading experts to discuss the latest information on how human genetics impacts drug response phenotypes. It presents not only the basic principles of pharmacogenetics, but also clinically valuable examples that cover a broad range of specialties and therapeutic areas. The first section of the book outlines critical concepts in pharmacogenetics and pharmacogenomics, including genetic testing, genotyping technologies, and adverse drug effects. The next section discusses the legal, ethical, and social implications of pharmacogenomics. The second half of the book details many of the main therapeutic areas, including oncologic drugs, cardiovascular drugs, statins, drug-induced long QT syndrome, diabetes drugs, respiratory drugs, gastrointestinal drugs, rheumatoid arthritis drugs, obstetric drugs, psychiatric drugs, pain and anesthesia drugs, HIV and antiretroviral drugs, pediatrics, and fetal and neonatal medicine. This textbook is an invaluable introduction to pharmacogenetics and pharmacogenomics for health care professionals, medical students, pharmacy students, graduate students and researchers in the biosciences. RESOURCES @ www.cambridge.org/altman - Link to the Pharmacogenomics Knowledgebase - study guides - images from the book - discussion questions - content updates., The study of pharmacogenetics and pharmacogenomics focuses on how our genes and complex gene systems influence our response to drugs. Recent progress in clinical therapeutics has led to the discovery of new biomarkers that make it technically easier to identify groups of patients which are more or less likely to respond to individual therapies. The aim is to improve personalised medicine - not simply to prescribe the right medicine, but to deliver the right drug at the right dose at the right time. This textbook brings together leading experts to discuss the latest information on how human genetics impacts drug response phenotypes. It presents not only the basic principles of pharmacogenetics, but also clinically valuable examples that cover a broad range of specialties and therapeutic areas. This textbook is an invaluable introduction to pharmacogenetics and pharmacogenomics for health care professionals, medical students, pharmacy students, graduate students and researchers in the biosciences., The study of pharmacogenetics and pharmacogenomics focuses on how our genes and complex gene systems influence our response to drugs. This textbook discusses the latest information on how human genetics impacts drug response phenotypes, for health care professionals, medical students, pharmacy students, graduate students and researchers in the biosciences.
LC Classification Number
RM301.3.G45 P76 2012

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