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Multifaceted Roles of Crystallography in Modern Drug Discovery by Eddy Arnold, Giovanna Scapin, Disha Patel (Paperback, 2015)

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The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development. Topics discussed include: drug design against complex systems (membrane proteins, cell surface receptors, epigenetic targets, and ribosomes); modulation of protein-protein interactions; the impact of small molecule structures in drug discovery and the application of concepts such as molecular geometry, conformation, and flexibility to drug design; methodologies for understanding and characterizing protein states and protein-ligand interactions during the drug design process; and monoclonal antibody therapies. These methods are illustrated through their application to problems of medical and biological significance, such as viral and bacterial infections, diabetes, autoimmune disease, and CNS diseases. As approaches to drug discovery have changed over time, so have the methodologies used to solve the varied, new, and difficult problems encountered in drug discovery. In recent years we have seen great progress in the fields of genetics, biology, chemistry, and medicine, but there are still many unmet medical needs, from bacterial infections to cancer to chronic maladies, that require novel, different, or better therapies. This work will be of interest to researchers and policy makers interested in the latest developments in drug design.

Product Identifiers

Publisher
Springer
ISBN-13
9789401797245
eBay Product ID (ePID)
209121884

Product Key Features

Author
Eddy Arnold, Giovanna Scapin, Disha Patel
Publication Name
Multifaceted Roles of Crystallography in Modern Drug Discovery
Format
Paperback
Language
English
Subject
Medicine, Chemistry, Biology, Physics
Publication Year
2015
Type
Textbook
Number of Pages
240 Pages

Dimensions

Item Height
235mm
Item Width
155mm
Item Weight
3869g

Additional Product Features

Series Title
Nato Science for Peace and Security Series A: Chemistry and Biology
Country/Region of Manufacture
Netherlands
Editor
Eddy Arnold, Giovanna Scapin, Disha Patel

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Multifaceted Roles of Crystallography in Modern Drug Discovery by Eddy Arnold, Giovanna Scapin, Disha Patel (Paperback, 2015)

About this product

Product Information

Product Identifiers

Product Key Features

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Additional Product Features

Best Selling in Adult Learning & University

Permaculture: A Designer's Manual by Bill Mollison (Hardcover, 1988)

Australian Native Bee Book: Keeping Stingless Bee Hives for Pets, Pollination and Sugarbag Honey by Tim Heard (Paperback, 2015)

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